Short Report - Birth Weight is Not Associated With Cataracts or Pseudophakia - Results from the Gutenberg Health Study.

Clinical ophthalmology (Auckland, N.Z.) Pub Date : 2025-01-16 eCollection Date: 2025-01-01 DOI:10.2147/OPTH.S502181

Achim Fieß, Sandra Gißler, Stephanie Grabitz, Philipp S Wild, Karl J Lackner, Manfred E Beutel, Michael S Urschitz, Oliver Tüscher, Thomas Münzel, Jörn M Schattenberg, Stavros V Konstantinides, Norbert Pfeiffer, Alexander K Schuster

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Abstract

This study investigates the association between self-reported birth weight (BW) and the frequency of cataract and pseudophakia in a large population-based cohort in Germany, as part of the Gutenberg Health Study (GHS). Slit lamp examination and Scheimpflug imaging of 8205 participants, aged 35 to 74, were assessed and signs of cataract or pseudophakia analyzed. The research aimed to explore the correlation between fetal growth restriction and/or prematurity indicated by BW and the frequency of cataract and pseudophakia. In the univariable analysis, cataract was initially associated with low and high BW, but this association disappeared after adjusting for age, sex, examiner and cardiovascular risk factors. No association was found between low BW and pseudophakia or the frequency of cataract surgery within 5 years. The study reveals novel insights from a large population-based study specifically exploring this association.

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短报告-出生体重与白内障或假性白内障无关-来自古腾堡健康研究的结果。

作为古登堡健康研究（GHS）的一部分，本研究调查了德国一个以人口为基础的大型队列中自我报告的出生体重（BW）与白内障和假性晶状体发病率之间的关系。对8205名年龄在35岁至74岁的参与者进行裂隙灯检查和Scheimpflug成像，并分析白内障或假性晶状体的征象。本研究旨在探讨BW指示的胎儿生长受限和/或早产与白内障和假性晶状体发生率的相关性。在单变量分析中，白内障最初与低体重和高体重相关，但在调整年龄、性别、检查者和心血管危险因素后，这种关联消失。低BW与假性晶状体或5年内白内障手术的频率没有关联。这项研究揭示了一项专门探索这种关联的大型基于人群的研究的新见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical ophthalmology (Auckland, N.Z.)

CiteScore

4.10

自引率

0.00%

发文量