Chapter 3: Impact of primary hyperparathyroidism

IF 2.9 3区医学 Q3 ENDOCRINOLOGY & METABOLISM

Annales d'endocrinologie Pub Date : 2025-02-01 DOI:10.1016/j.ando.2025.101692

Nicolas Scheyer , Samuel Frey , Eugénie Koumakis , Carole Guérin , Rachel Desailloud , Lionel Groussin , Bertrand Cariou , Bruno Vergès , Laurent Brunaud , Eric Mirallié , Lucile Figueres , Hélène Lasolle

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Abstract

At present, primary hyperparathyroidism is most often discovered in an asymptomatic patient, but can sometimes be revealed by a renal or bone complications. In all cases, a full work-up is recommended, with assessment of renal function (glomerular filtration rate), 24-hour calciuria, screening for risk factors for lithiasis, and renal and urinary tract imaging (ultrasound or CT scan) to look for stones or nephrocalcinosis. Bone densitometry, with measurements of the spine, femur and radius, is the recommended reference test for demineralization. Standard X-rays of the spine or other imaging techniques are recommended for the detection of asymptomatic vertebral fracture. Neurocognitive manifestations, reduced quality of life or cardiovascular manifestations should not be routinely screened for, as they are not currently consensual criteria for surgical indications.

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第三章：原发性甲状旁腺功能亢进的影响。

目前，原发性甲状旁腺功能亢进最常在无症状患者中发现，但有时可通过肾脏或骨骼并发症显示。在所有病例中，建议进行全面检查，评估肾功能（肾小球滤过率），24小时尿钙，筛查结石的危险因素，以及肾脏和尿路成像（超声或CT扫描）以寻找结石或肾钙质沉着症。骨密度测量，包括脊柱、股骨和桡骨的测量，是推荐的脱矿参考测试。标准的脊柱x光片或其他成像技术被推荐用于检测无症状的椎体骨折。神经认知表现、生活质量下降或心血管表现不应常规筛查，因为它们目前不是手术指征的共识标准。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annales d'endocrinologie 医学-内分泌学与代谢

CiteScore

4.40

自引率

6.50%

发文量

311

审稿时长

50 days

期刊介绍： The Annales d''Endocrinologie, mouthpiece of the French Society of Endocrinology (SFE), publishes reviews, articles and case reports coming from clinical, therapeutic and fundamental research in endocrinology and metabolic diseases. Every year, it carries a position paper by a work-group of French-language endocrinologists, on an endocrine pathology chosen by the Society''s Scientific Committee. The journal is also the organ of the Society''s annual Congress, publishing a summary of the symposia, presentations and posters. "Les Must de l''Endocrinologie" is a special booklet brought out for the Congress, with summary articles that are always very well received. And finally, we publish the high-level instructional courses delivered during the Henri-Pierre Klotz International Endocrinology Days. The Annales is a window on the world, keeping alert clinicians up to date on what is going on in diagnosis and treatment in all the areas of our specialty.