Effects of warning information at medication initiation on deprescribing intentions in older adults: A hypothetical vignette

IF 2.9 2区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Patient Education and Counseling Pub Date : 2025-01-10 DOI:10.1016/j.pec.2025.108654

Sarah E. Vordenberg , Kari Ostaszewski , Vincent D. Marshall , Brian J. Zikmund-Fisher , Kristie Rebecca Weir

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引用次数: 0

Abstract

Objectives

To explore to what degree providing patients warning information about the long-term risks of a medication would affect their subsequent desire to discontinue it.

Methods

We conducted a vignette-based online experiment in which participants aged ≥ 65 years from the United States were asked to imagine starting and subsequently stopping omeprazole. Participants were randomized to one of four vignettes about starting omeprazole (potential long-term harms or no harm information; OTC vs. prescription). Participants reported interest in stopping omeprazole on a 6-point Likert scale. We calculated descriptive statistics and used logistic regression to compare participants with high (scores 4–6) versus low agreement (scores 1–3) with stopping.

Results

Participants (n = 1245) had a median age of 70 years. After adjusting for demographic characteristics, older adults who received warning information when starting the medication were more likely to agree to stop omeprazole (OR 1.21, 95 % C.I. 1.02, 1.43). Willingness to stop omeprazole was higher among women (vs. men), among respondents with higher literacy, and among those who had never or previously used PPIs (vs current use).

Conclusion

Warning information about potential long-term risks when initiating a medication may increase the likelihood of subsequently stopping a medication when recommended by a PCP.

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开始用药时警告信息对老年人处方意图的影响：一个假设的小插曲。

目的：探讨向患者提供药物长期风险的警告信息在多大程度上影响他们随后的停药意愿。方法：我们进行了一项基于小视频的在线实验，要求年龄≥ 65岁的美国参与者想象开始和随后停止奥美拉唑。参与者被随机分配到四个关于开始服用奥美拉唑的小插曲中的一个(潜在的长期危害或没有危害信息；OTC vs.处方)。参与者报告对停止奥美拉唑的兴趣为6分李克特量表。我们计算了描述性统计数据，并使用逻辑回归来比较高（4-6分）和低（1-3分）的参与者是否停止。结果：参与者（n = 1245）的中位年龄为70岁。在调整人口统计学特征后，在开始用药时收到警告信息的老年人更有可能同意停用奥美拉唑（OR 1.21, 95 % C.I. 1.02, 1.43）。女性（与男性相比）、文化程度较高的受访者以及从未或以前使用过PPIs的受访者（与目前使用的受访者相比）停用奥美拉唑的意愿更高。结论：在开始用药时关于潜在长期风险的警告信息可能会增加随后在PCP推荐下停药的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Patient Education and Counseling 医学-公共卫生、环境卫生与职业卫生

CiteScore

5.60

自引率

11.40%

发文量

384

审稿时长

46 days

期刊介绍： Patient Education and Counseling is an interdisciplinary, international journal for patient education and health promotion researchers, managers and clinicians. The journal seeks to explore and elucidate the educational, counseling and communication models in health care. Its aim is to provide a forum for fundamental as well as applied research, and to promote the study of organizational issues involved with the delivery of patient education, counseling, health promotion services and training models in improving communication between providers and patients.