{"title":"The Link between Oxygen and Basement Membranes.","authors":"Colin D McCaig","doi":"10.1007/978-3-031-68827-0_8","DOIUrl":null,"url":null,"abstract":"<p><p>Epithelial tissues and the basement membranes they sit on did not appear for billions of years. Their appearance was delayed most likely by a lack of oxygen, which is required for collagen synthesis, and which only began to build up following the Great Oxygenation Event ~ 2.4 billion years ago. Both the oxygenation of Earth and the multiple roles of collagen require regulation by electrical forces.</p>","PeriodicalId":21169,"journal":{"name":"Reviews of Physiology Biochemistry and Pharmacology","volume":"187 ","pages":"61-87"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reviews of Physiology Biochemistry and Pharmacology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/978-3-031-68827-0_8","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Biochemistry, Genetics and Molecular Biology","Score":null,"Total":0}
引用次数: 0
Abstract
Epithelial tissues and the basement membranes they sit on did not appear for billions of years. Their appearance was delayed most likely by a lack of oxygen, which is required for collagen synthesis, and which only began to build up following the Great Oxygenation Event ~ 2.4 billion years ago. Both the oxygenation of Earth and the multiple roles of collagen require regulation by electrical forces.
期刊介绍:
The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.