Synaptic Physiology Depends on Electrical Forces and Liquid-Liquid Phase Separation.

2区医学 Q1 Biochemistry, Genetics and Molecular Biology

Reviews of Physiology Biochemistry and Pharmacology Pub Date : 2025-01-01 DOI:10.1007/978-3-031-68827-0_17

Colin D McCaig

引用次数: 0

Abstract

Pre- and post-synaptic events are regulated by liquid-liquid phase separation and this phenomenon requires multiple electrical forces. Both axonal transport and the organization of postsynaptic excitatory and inhibitory receptors are regulated by LLPS, with its mandatory electrical drivers ultimately determining our cognitive health and capacity.

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突触生理学依赖于电作用力和液-液相分离。

突触前和突触后事件是由液-液相分离调控的，这种现象需要多种电作用力。轴突转运和突触后兴奋性和抑制性受体的组织都受到LLPS的调节，其强制性的电驱动最终决定了我们的认知健康和能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Reviews of Physiology Biochemistry and Pharmacology 医学-生化与分子生物学

CiteScore

11.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The highly successful Reviews of Physiology, Biochemistry and Pharmacology continue to offer high-quality, in-depth reviews covering the full range of modern physiology, biochemistry and pharmacology. Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.