Extracting the fingerprints of sequences of random rhythmic auditory stimuli from electrophysiological data.

IF 3.8 2区 生物学 Q1 BIOCHEMICAL RESEARCH METHODS
PLoS Computational Biology Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI:10.1371/journal.pcbi.1012765
Fernando A Najman, Antonio Galves, Marcela Svarc, Claudia D Vargas
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引用次数: 0

Abstract

It has been classically conjectured that the brain assigns probabilistic models to sequences of stimuli. An important issue associated with this conjecture is the identification of the classes of models used by the brain to perform this task. We address this issue by using a new clustering procedure for sets of electroencephalographic (EEG) data recorded from participants exposed to a sequence of auditory stimuli generated by a stochastic chain. This clustering procedure indicates that the brain uses the recurrent occurrences of a regular auditory stimulus in order to build a model.

从电生理数据中提取随机节奏性听觉刺激序列指纹图谱。
经典的推测是,大脑为刺激序列分配了概率模型。与这一猜想相关的一个重要问题是识别大脑执行这一任务所使用的模型类别。我们通过使用新的聚类程序来解决这个问题,这些聚类程序记录了参与者暴露于随机链产生的听觉刺激序列的脑电图(EEG)数据集。这种聚类过程表明,大脑利用常规听觉刺激的反复出现来建立一个模型。
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来源期刊
PLoS Computational Biology
PLoS Computational Biology BIOCHEMICAL RESEARCH METHODS-MATHEMATICAL & COMPUTATIONAL BIOLOGY
CiteScore
7.10
自引率
4.70%
发文量
820
审稿时长
2.5 months
期刊介绍: PLOS Computational Biology features works of exceptional significance that further our understanding of living systems at all scales—from molecules and cells, to patient populations and ecosystems—through the application of computational methods. Readers include life and computational scientists, who can take the important findings presented here to the next level of discovery. Research articles must be declared as belonging to a relevant section. More information about the sections can be found in the submission guidelines. Research articles should model aspects of biological systems, demonstrate both methodological and scientific novelty, and provide profound new biological insights. Generally, reliability and significance of biological discovery through computation should be validated and enriched by experimental studies. Inclusion of experimental validation is not required for publication, but should be referenced where possible. Inclusion of experimental validation of a modest biological discovery through computation does not render a manuscript suitable for PLOS Computational Biology. Research articles specifically designated as Methods papers should describe outstanding methods of exceptional importance that have been shown, or have the promise to provide new biological insights. The method must already be widely adopted, or have the promise of wide adoption by a broad community of users. Enhancements to existing published methods will only be considered if those enhancements bring exceptional new capabilities.
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