A patient choice-driven lifestyle intervention lowers HbA1c in type 2 diabetes: A feasibility study.

IF 2.2 Q3 PHYSIOLOGY
Nathan R Weeldreyer, Mindy L McEntee, Matthew P Martin, Chong D Lee, Farshad Fani Marvasti, Glenn A Gaesser, Rodger Kessler, Siddhartha S Angadi
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Abstract

Type 2 diabetes (T2D) is a common metabolic disorder in which only 25% of patients meet management targets. While the primary care setting is positioned to provide lifestyle management education, studies are lacking which integrate behavior interventions in this setting utilizing clinic staff. Thus, we evaluated a 90-day lifestyle intervention for management of glycemia at a family practice clinic administered by clinic medical assistants. Twenty patients with non-insulin-dependent T2D completed a 90-day intervention driven by patient choices of nutrition and physical activity. Medical assistants were trained by members of the study team and administered the intervention under nurse practitioner supervision. HbA1c trended toward significant reduction 8.59 ± 0.9% to 8.15 ± 1.2% (p = 0.051, 95% CI: -0.88 to 0.003). Modest reductions were observed for waist circumference (115.5 ± 12.6 vs. 112.5 ± 15.2 cm; p = 0.014, 95% CI: -5.66 to -0.26), body weight (97.7 ± 21.9 vs. 95.6 ± 23.9 kg; p = 0.016. 95% CI: -3.84 to -0.31), and BMI (33.7 ± 7.2 vs. 32.8 ± 7.5 kg/m2; p = 0.028, 95% CI: -1.29 to -0.12). This 90-day, patient choice-intervention was successful at lowering HbA1c in patients with T2D. Our study is limited by a lack of control group, and results should be interpreted as such. These data have implications for team-based care models in clinic settings to improve health outcomes in patients with T2D.

患者选择驱动的生活方式干预降低2型糖尿病患者的HbA1c:一项可行性研究
2型糖尿病(T2D)是一种常见的代谢紊乱,其中只有25%的患者达到管理目标。虽然初级保健机构的定位是提供生活方式管理教育,但缺乏利用临床工作人员在这种情况下整合行为干预的研究。因此,我们评估了由临床医疗助理管理的家庭诊所的90天生活方式干预对血糖的管理。20名非胰岛素依赖型T2D患者完成了为期90天的干预,干预由患者选择的营养和身体活动驱动。医疗助理由研究小组成员进行培训,并在执业护士的监督下实施干预。HbA1c倾向于显著降低8.59±0.9%至8.15±1.2% (p = 0.051, 95% CI: -0.88至0.003)。腰围略有减少(115.5±12.6 vs 112.5±15.2 cm);p = 0.014, 95%置信区间CI: -5.66 - -0.26)、体重(97.7±21.9和95.6±23.9公斤;p = 0.016。95%置信区间:-3.84 - -0.31),和体重指数(33.7±7.2和32.8±7.5 kg / m2;p = 0.028, 95% CI: -1.29 ~ -0.12)。这项为期90天的患者选择干预成功地降低了T2D患者的HbA1c。我们的研究因缺乏对照组而受到限制,结果应如此解释。这些数据对临床环境中以团队为基础的护理模式具有启示意义,可以改善t2dm患者的健康结果。
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来源期刊
Physiological Reports
Physiological Reports PHYSIOLOGY-
CiteScore
4.20
自引率
4.00%
发文量
374
审稿时长
9 weeks
期刊介绍: Physiological Reports is an online only, open access journal that will publish peer reviewed research across all areas of basic, translational, and clinical physiology and allied disciplines. Physiological Reports is a collaboration between The Physiological Society and the American Physiological Society, and is therefore in a unique position to serve the international physiology community through quick time to publication while upholding a quality standard of sound research that constitutes a useful contribution to the field.
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