Impact of 3D-Printed Models for Surgical Planning in Renal Cell Carcinoma With Venous Tumor Thrombus: A Randomized Multicenter Clinical Trial.

IF 5.9 2区医学 Q1 UROLOGY & NEPHROLOGY

Journal of Urology Pub Date : 2025-05-01 Epub Date: 2025-01-21 DOI:10.1097/JU.0000000000004425

I Rivero Belenchón, C B Congregado Ruíz, G Gómez Ciriza, V Gómez Dos Santos, F J Burgos Revilla, R A Medina López

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引用次数: 0

Abstract

Purpose: Our goal was to determine whether surgical planning based on 3D models allows for better surgical outcomes than conventional surgical planning in (1) complications, (2) surgical time, and (3) hospital stay.

Materials and methods: This multicenter clinical trial (NCT03738488) included 66 patients diagnosed with renal cell carcinoma and venous thrombus extension who underwent nephrectomy with thrombectomy. Patients were randomized 1:1 to (1) surgical planning with conventional images (control group) and (2) surgical planning with 3D-printed models (experimental group). We compared the surgical outcomes of each group in (1) complications, (2) surgical time, and (3) hospital stay.

Results: The mean surgical time and the mean hospital stay were similar between the groups, although there were more patients with no ICU stay in the 3D group (17, 52%) than in the image group (odds ratio [OR]: 3.32 [1.16-9.48]). There were more patients without any complications in the 3D group (n = 18; OR: 5.40 [1.16-16.53]), and among those with complications, they were more severe in the imaging group (n = 16; OR: 20.46 [2.33-178.20]).

Conclusions: Surgical planning with 3D printing in renal cell carcinoma and venous thrombus extension compared with conventional planning showed a lower ratio of postoperative complications that helped decrease the ICU stay.

Trial registration: ClinicalTrials.gov:NCT03738488.

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3d打印模型对肾细胞癌合并静脉肿瘤血栓手术计划的影响。一项随机多中心临床试验。

目的：确定基于3D模型的手术计划是否比传统手术计划在1)并发症、2)手术时间和3)住院时间方面有更好的手术效果。材料和方法：本多中心临床试验（NCT03738488）纳入66例诊断为肾细胞癌并静脉血栓扩展的患者，行肾切除术并取栓术。患者按1:1随机分为：1)常规影像手术计划组（对照组）和2)3d打印模型手术计划组（实验组）。我们从1)并发症、2)手术时间和3)住院时间三个方面比较各组的手术结果。结果：两组间平均手术时间和平均住院时间相似，但3D组无ICU住院患者17例（52%）多于图像组（OR: 3.32(1.16-9.48)）。无并发症的3D组患者较多（n=18）（OR: 5,40(1,16-16,53)），出现并发症的影像学组患者较多（n=16）（OR: 20,46(2,33-178,20)）。结论：与常规方案相比，采用3D打印技术进行肾细胞癌和静脉血栓扩展手术方案的术后并发症发生率较低，有助于减少ICU住院时间。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Urology 医学-泌尿学与肾脏学

CiteScore

11.50

自引率

7.60%

发文量

3746

审稿时长

2-3 weeks

期刊介绍： The Official Journal of the American Urological Association (AUA), and the most widely read and highly cited journal in the field, The Journal of Urology® brings solid coverage of the clinically relevant content needed to stay at the forefront of the dynamic field of urology. This premier journal presents investigative studies on critical areas of research and practice, survey articles providing short condensations of the best and most important urology literature worldwide, and practice-oriented reports on significant clinical observations.