A Review on the Applications of Quantum Dots in Sample Preparation

Abstract

In recent years, despite significant advances in preconcentration and preparation techniques that have led to efficient recovery and accurate measurement of target compounds. There is still a need to develop adsorbents with unique and efficient features such as high pore volume and surface area, reactivity, easy synthesis, low toxicity, and compatibility with the environment, which increase the adsorption capacity and increase extraction efficiency. Semiconductor nanocrystals called quantum dots (QDs) with a size of less than 10 nm are three-dimensional nanoparticles with a spherical, rod, or disc structure that have significant potential in extraction as adsorbents due to their excellent properties such as low toxicity, reactivity, environmental friendliness, and hydrophilic and hydrophobic interactions. One of the most basic issues in the development of adsorbents is to increase the effective surface and, as a result, their extraction efficiency. QDs, having an effective surface much higher than conventional nanomaterials, are a suitable option for extracting target compounds in different environments. This work comprehensively reviews QD-based extraction methods and surface modification strategies of QDs based on functional groups, ligands, and materials from 2013 to 2024. In addition, the applications of QD-based composites for the extraction of organic and inorganic analytes (residues of drugs in human blood and plasma, toxins, pesticides, pollutants from chemical industries, heavy metals, etc.) in different matrices are investigated.