Validation of Spatial Orientation Screening questionnaire for use in memory clinic patients.

IF 3.4 3区医学 Q2 NEUROSCIENCES

Journal of Alzheimer's Disease Pub Date : 2025-01-15 DOI:10.1177/13872877241308877

Gro Gujord Tangen, Knut Engedal, Karin Persson, Geir Selbæk, Shams Dakhil, Riona McArdle, Marit Mjørud, Janne Røsvik, Anne Marit Mengshoel, Anne Brita Knapskog

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引用次数: 0

Abstract

Background: Spatial orientation is required for independent mobility in society. Deficits in spatial orientation can be an early symptom of Alzheimer's disease and other dementias, and there is a need for brief assessment tools to identify impairments.

Objective: The aim of this study was to evaluate the construct and known-group validity of our newly developed Spatial Orientation Screening (SOS) questionnaire.

Methods: We included 132 patients with subjective cognitive decline (n = 16), mild cognitive impairment (n = 32), or all-cause dementia (n = 84) from a memory clinic and a reference group of cognitively unimpaired older adults (n = 108). The patients and their next-of-kin answered the self- and proxy-rated versions of the 4-item SOS (0-8 points) and the 10-item Questionnaire of Everyday Navigational Ability (QuENA, 0-30 points). The patients also performed the Floor Maze Test (FMT) for performance-based spatial abilities.

Results: Mean ages (SD) of the patient and reference groups were 68.6 (±7.6) years and 73.7 (±6.7) years, respectively. Construct validity between self-rated versions of the SOS and QuENA was satisfactory with r_s= 0.66, between the proxy-rated versions r_s= 0.61, and between the proxy-reported SOS and FMT r_s= 0.49 (all p < 0.001). Known-group validity was also acceptable, with significantly higher median (IQR) SOS self-reported scores in patients 1.0 (2.0) compared to the reference group 0.2 (0.5) points, (p < 0.001). Informants reported more severe impairments compared to the patients' self-reports on both SOS and QuENA (both p < 0.001).

Conclusions: The SOS had satisfactory validity for use as a screening instrument for assessment of spatial orientation in memory clinic patients.

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空间取向筛选问卷在临床记忆病人中的应用验证。

背景：空间定向是社会中独立行动所必需的。空间定向缺陷可能是阿尔茨海默病和其他痴呆症的早期症状，因此需要一种简短的评估工具来识别损伤。目的：本研究的目的是评估我们新开发的空间取向筛选（SOS）问卷的结构和已知组效度。方法：我们纳入了132例主观认知能力下降（n = 16）、轻度认知障碍（n = 32）或全因痴呆（n = 84）的患者，这些患者来自记忆诊所和一组认知功能未受损的老年人（n = 108）。患者及其近亲属分别回答4项SOS（0-8分）和10项日常导航能力问卷（QuENA， 0-30分）的自评版和代理版。患者还进行了基于表现的空间能力的地板迷宫测试（FMT）。结果：患者组和对照组的平均年龄（SD）分别为68.6（±7.6）岁和73.7（±6.7）岁。自评版的SOS与QuENA的建构效度令人满意，rs = 0.66；代理评版的SOS与FMT的建构效度令人满意，rs = 0.61；代理报告版的SOS与FMT的建构效度均为0.49。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Alzheimer's Disease 医学-神经科学

CiteScore

6.40

自引率

7.50%

发文量

1327

审稿时长

2 months

期刊介绍： The Journal of Alzheimer''s Disease (JAD) is an international multidisciplinary journal to facilitate progress in understanding the etiology, pathogenesis, epidemiology, genetics, behavior, treatment and psychology of Alzheimer''s disease. The journal publishes research reports, reviews, short communications, hypotheses, ethics reviews, book reviews, and letters-to-the-editor. The journal is dedicated to providing an open forum for original research that will expedite our fundamental understanding of Alzheimer''s disease.