Epidemiological study of HPV infection in 24,588 rural women in Luonan, China

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY

Gynecologic Oncology Reports Pub Date : 2025-02-01 DOI:10.1016/j.gore.2024.101669

Xin Zhao , Shi Shen , Cailing Su , Juan Chang , Yunfang Yan , Jianmin Zhao

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引用次数: 0

Abstract

Cervical cancer is a significant public health issue for women, with human papillomavirus (HPV) infection rates exhibiting regional variations throughout China. This study examined data from a cohort of 24,588 rural women who engaged in cervical cancer screening in Luonan County from 2021 to 2023, utilizing high-risk HPV (hrHPV) testing methodologies. The findings revealed an overall HPV positivity rate of 14.18 %, with hrHPV positivity rates of 13.99 % in 2021, 12.97 % in 2022, and 15.32 % in 2023. Infection rates increased with age, showing significant differences among age groups. Types 52, 16, and 58 were the most prevalent hrHPV types. Single-type infections were more common than multiple infections, with prevalent combinations such as HPV16 + HPV52, HPV52 + HPV58, and HPV51 + HPV16. The results highlight the imperative for improved screening, especially for women aged 60 to 64 residing in rural areas, and emphasize the importance of HPV vaccination and targeted screening for the prevention and eventual eradication of cervical cancer.

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罗南市24588名农村妇女HPV感染流行病学研究

宫颈癌是妇女面临的重大公共卫生问题，人乳头瘤病毒（HPV）感染率在中国各地表现出地区差异。本研究采用高危HPV （hrHPV）检测方法，对2021年至2023年在罗南县从事宫颈癌筛查的24,588名农村妇女进行了数据分析。研究结果显示，总体HPV阳性率为14.18%，其中hrHPV阳性率在2021年为13.99%，2022年为12.97%，2023年为15.32%。感染率随年龄增长而增加，各年龄组之间存在显著差异。52型、16型和58型是最常见的hrHPV类型。单型感染比多型感染多见，以HPV16 + HPV52、HPV52 + HPV58、HPV51 + HPV16为主。研究结果强调了改善筛查的必要性，特别是对居住在农村地区的60至64岁妇女，并强调了HPV疫苗接种和有针对性筛查对预防和最终根除宫颈癌的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Gynecologic Oncology Reports OBSTETRICS & GYNECOLOGY-

CiteScore

2.00

自引率

0.00%

发文量

183

审稿时长

41 days

期刊介绍： Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.