Phenol Dilution With Saline Solution Versus Alcohol in Partial Matricectomy for Onychocryptosis.

IF 2.5 3区医学 Q2 DERMATOLOGY

Dermatologic Surgery Pub Date : 2025-01-16 DOI:10.1097/DSS.0000000000004541

Joaquín Espiñeira Sicre, Lucía García Sirvent, Juan Ruiz Sánchez, Pedro Álvarez Chinchilla, Laura García Fernández, Julia Miralles Botella

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引用次数: 0

Abstract

Background: Onychocryptosis significantly impacts quality of life. Chemical partial matricectomy with phenol is a common surgical treatment. The use of alcohol as a solvent during this procedure has been controversial. In vitro studies suggest that physiologic saline solution (PSS) may be a more effective solvent for phenol.

Objective: To evaluate the in vivo efficacy of PSS as a phenol solvent, in terms of postoperative outcomes, compared to alcohol.

Methods: A retrospective unicentric cohort study was conducted on patients who underwent partial chemical matricectomy with phenol for onychocryptosis. Sociodemographic and clinical variables were collected and compared between the alcohol and PSS groups. Clinical staging followed Martinez Nova and colleagues' classification. Patients were followed up over a 12-month period to assess postoperative complications.

Results: The study population demonstrated typical characteristics of onychocryptosis, with a median age of 20 years. No statistically significant differences were found between the groups in terms of pain, infections, or bleeding postoperatively. There were also no differences in terms of recurrence, days of analgesic use, or need for antibiotic therapy (p > .05).

Conclusion: The results suggest that PSS is as effective and safe as alcohol as a solvent for phenol in chemical partial matricectomy.

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苯酚稀释盐水溶液与酒精在部分基质切除术治疗足趾塌陷的比较。

背景：甲爪塌陷显著影响生活质量。苯酚化学部分基质切除术是一种常用的手术治疗方法。在此过程中使用酒精作为溶剂一直存在争议。体外研究表明生理盐水溶液（PSS）可能是苯酚更有效的溶剂。目的：评价PSS作为苯酚溶剂在体内的术后疗效，并与酒精进行比较。方法：一项回顾性单中心队列研究，对接受部分化学基质切除术的患者进行了苯酚治疗甲爪麻痹。收集社会人口学和临床变量，比较酒精组和PSS组之间的差异。临床分期遵循Martinez Nova及其同事的分类。患者随访12个月以评估术后并发症。结果：研究人群表现出典型的甲爪塌陷特征，中位年龄为20岁。两组在术后疼痛、感染或出血方面无统计学差异。在复发率、镇痛药使用天数或抗生素治疗需求方面也无差异（p < 0.05）。结论：PSS在化学部分基质切除术中作为苯酚的溶剂与乙醇一样安全有效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dermatologic Surgery 医学-皮肤病学

CiteScore

3.10

自引率

16.70%

发文量

547

期刊介绍： Exclusively devoted to dermatologic surgery, the Dermatologic Surgery journal publishes the most clinically comprehensive and up-to-date information in its field. This unique monthly journal provides today’s most expansive and in-depth coverage of cosmetic and reconstructive skin surgery and skin cancer through peer-reviewed original articles, extensive illustrations, case reports, ongoing features, literature reviews and correspondence. The journal provides information on the latest scientific information for all types of dermatologic surgery including: -Ambulatory phlebectomy- Blepharoplasty- Body contouring- Chemical peels- Cryosurgery- Curettage and desiccation- Dermabrasion- Excision and closure- Flap Surgery- Grafting- Hair restoration surgery- Injectable neuromodulators- Laser surgery- Liposuction- Microdermabrasion- Microlipoinjection- Micropigmentation- Mohs micrographic surgery- Nail surgery- Phlebology- Sclerotherapy- Skin cancer surgery- Skin resurfacing- Soft-tissue fillers. Dermatologists, dermatologic surgeons, plastic surgeons, oculoplastic surgeons and facial plastic surgeons consider this a must-read publication for anyone in the field.