Recurrent relapsing remitting Serratia marcescens infective endocarditis in a former drug-using patient

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2025-01-10 DOI:10.1016/j.diagmicrobio.2025.116682

Monique Boukobza , Richard Raffoul , Jean-Pierre Laissy

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引用次数: 0

Abstract

Unusual course of Serratia marcescens (SM) infectious endocarditis (IE) and literature review (2016-2024; 26 cases).

A 44-year-old man, with chronic venous ulcers, presented 21/2 years after a MSSA tricuspid valve IE, a tricuspid and aortic valves SM IE . After 6 weeks of antibiotherapy (meropenem i.v., 2 g/6 h), he presented a relapse (same sensitivity pattern), complicated by tibio-peroneal trunk aneurysm. He underwent a biological tricuspid valve replacement.

Fifteen months later, he presented a recurrent SM IE, (same sensitivity pattern), complicated by a popliteal artery aneurysm. An aortic-tricuspid bioprosthetic valve replacement was performed. At one-year, there was no sign infection.

The occurrence of both relapsing and recurrence, and of infectious aneurysms in SM IE are highlighted. However, these findings must be interpreted with caution, due to the lack of molecular typing.

Literature shows that a regimen combining a beta-lactam and either fluoroquinolone or an aminoglycoside seems to warrant a less mortality rate.

查看原文本刊更多论文

前用药患者复发复发缓解粘质沙雷菌感染性心内膜炎。

粘质沙雷菌感染性心内膜炎（IE）异常病程及文献回顾（2016-2024）26例)。一名44岁男性，慢性静脉溃疡，在MSSA三尖瓣IE，三尖瓣和主动脉瓣SM IE后两年半出现。抗生素治疗6周后（美罗培南静脉注射，2g /6 h），复发（相同的敏感性模式），并发胫腓主干动脉瘤。他接受了生物三尖瓣置换术。15个月后，他再次出现SM - IE（同样的敏感性模式），并发腘动脉动脉瘤。行主动脉-三尖瓣生物瓣膜置换术。一年后，无感染迹象。强调了SM - IE中复发和复发以及感染性动脉瘤的发生率。然而，由于缺乏分子分型，这些发现必须谨慎解释。文献显示，将-内酰胺与氟喹诺酮或氨基糖苷联合使用的方案似乎可以保证较低的死亡率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.