Luminance invariant encoding in mouse primary visual cortex.

Abstract

The visual system adapts to maintain sensitivity and selectivity over a large range of luminance intensities. One way that the retina maintains sensitivity across night and day is by switching between rod and cone photoreceptors, which alters the receptive fields and interneuronal correlations of retinal ganglion cells (RGCs). While these adaptations allow the retina to transmit visual information to the brain across environmental conditions, the code used for that transmission varies. To determine how downstream targets encode visual scenes across light levels, we measured the effects of luminance adaptation on thalamic and cortical population activity. While changes in the retinal output are evident in the lateral geniculate nucleus (LGN), selectivity in the primary visual cortex (V1) is largely invariant to the changes in luminance. We show that the visual system could maintain sensitivity across environmental conditions without altering cortical selectivity through the convergence of parallel functional pathways from the thalamus to the cortex.