Effect of microemulsion system on water dispersibility and bioavailability of γ-oryzanol.

IF 1.4 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-01-15 DOI:10.1093/bbb/zbaf002

Junya Ito, Naoko Kumagai, Ayaka Suzuki, Naoki Shoji, Isabella Supardi Parida, Mamoru Takahashi, Kiyotaka Nakagawa

引用次数: 0

Abstract

This study developed water-dispersible γ-oryzanol (WD-OZ) using microemulsion system and assessed their absorption in rats. While γ-oryzanol itself is hardly soluble in water, WD-OZ exhibited high water dispersibility, and γ-oryzanol, along with its metabolites, was detected in rat plasma. These findings provide a solid basis for future application of the microemulsion-based approach to enhance the bioavailability of γ-oryzanol in food.

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微乳液体系对γ-谷维醇水分散性和生物利用度的影响。

本研究采用微乳法制备水分散型γ-谷米醇（WD-OZ），并测定其在大鼠体内的吸收情况。γ-谷维素本身不溶于水，但WD-OZ具有较高的水分散性，并且在大鼠血浆中检测到γ-谷维素及其代谢物。这些研究结果为今后应用微乳化方法提高γ-谷维素在食品中的生物利用度提供了坚实的基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bioscience, Biotechnology, and Biochemistry 生物-生化与分子生物学

CiteScore

3.50

自引率

0.00%

发文量

183

审稿时长

1 months

期刊介绍： Bioscience, Biotechnology, and Biochemistry publishes high-quality papers providing chemical and biological analyses of vital phenomena exhibited by animals, plants, and microorganisms, the chemical structures and functions of their products, and related matters. The Journal plays a major role in communicating to a global audience outstanding basic and applied research in all fields subsumed by the Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA).