Compact high-bandwidth single-beam optically-pumped magnetometer for biomagnetic measurement.

IF 2.9 2区 医学 Q2 BIOCHEMICAL RESEARCH METHODS
Biomedical optics express Pub Date : 2024-12-20 eCollection Date: 2025-01-01 DOI:10.1364/BOE.545624
Tianbo Wu, Wei Xiao, Xiang Peng, Teng Wu, Hong Guo
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引用次数: 0

Abstract

Optically-pumped magnetometer (OPM) has been of increasing interest for biomagnetic measurements due to its low cost and portability compared with superconducting quantum interference devices (SQUID). Miniaturized spin-exchange-relaxation-free (SERF) OPMs typically have limited bandwidth (less than a few hundred Hertz), making it difficult to measure high-frequency biomagnetic signals such as the magnetocardiography (MCG) signal of the mouse. Existing experiments mainly use SQUID systems to measure the signal. In this paper, we introduce a prototype miniaturized single-beam SERF magnetometer with a bandwidth of ∼ 1 kHz. Instead of operating the OPM in a closed-loop mode to improve the bandwidth of the OPM, which usually has a poorer performance in high-frequency range, we use the power-broadening effects to shorten the spin relaxation time and thus a faster response to the magnetic fields to be measured. Combined with light power stabilizations to improve both the sensitivity and stability, our magnetometer has a low noise floor of 30 fT / Hz1/2, which has been successfully adopted to measure the MCG signal of the mouse.

紧凑型高带宽单光束光泵磁力仪,用于生物磁力测量。
与超导量子干涉器件(SQUID)相比,光泵浦磁强计(OPM)由于其低成本和便携性而越来越受到生物磁测量领域的关注。小型化的无自旋交换弛豫(SERF) opm通常具有有限的带宽(小于几百赫兹),这使得测量高频生物磁信号(如小鼠的心脏磁图(MCG)信号)变得困难。现有的实验主要使用SQUID系统来测量信号。在本文中,我们介绍了一个带宽为1 kHz的小型化单束SERF磁强计原型。为了提高OPM的带宽(通常在高频范围内性能较差),我们使用功率展宽效应来缩短自旋弛豫时间,从而更快地响应待测磁场,而不是在闭环模式下操作OPM。结合光功率稳定来提高灵敏度和稳定性,我们的磁强计具有30 fT / Hz1/2的低本底噪声,已成功用于测量小鼠的MCG信号。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomedical optics express
Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS
CiteScore
6.80
自引率
11.80%
发文量
633
审稿时长
1 months
期刊介绍: The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.
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