Seroprevalence of and Associated Risk Factors for Bovine Viral Diarrhea in Dairy Cattle in and Around Nekemte Town, East Wallaga, Oromiya Regional State, Ethiopia.

Abstract

Bovine viral diarrhea virus (BVDV) is an important pathogen affecting dairy cattle all over the world by causing significant economic losses due to reproductive and respiratory problems, immunosuppressive effects, increased risk of morbidity, and calf mortality. A cross-sectional study was conducted from February 2021 to August 2021 to determine the seroprevalence of bovine viral diarrhea (BVD) and identify risk factors associated with its occurrence in and around Nekemte Town of Ethiopia. Blood samples were collected from 305 dairy cattle of 41 herds by using cluster-sampling method. All sampled animals were identified by their age, breeds, origin, parity, pregnancy status, and history of reproductive and respiratory problems. Competitive ELISA was used in the laboratory to detect the presence of antibodies in the serum. At the animal and herd level, descriptive statistics were utilized to assess the amount of BVDV viral antibody circulation, and multivariable logistic regression analysis was employed to detect potential risk variables. The result demonstrates 9.84% (95% confidence interval (CI): 6.49-13.18) and 28.52% (95% CI: 23.46-33.59) seroprevalence of BVDV antibody at individual and herd level, respectively. Abortion (odds ratio (OR) = 2.75; p = 0.019), retention of fetal membrane (OR = 3.33; p = 0.011), purchasing of animals (OR = 2.98; p = 0.017), and pregnancy (OR = 3.16; p = 0.019) were variables significantly associated with the seropositivity of BVDV. Herd size was found to be substantially linked with BVDV infection at the herd level (p = 0.009). These moderate seroprevalence of BVDV results indicate that the virus is widely spread among dairy cattle at various farms in and around Nekemte Town, hurting dairy farm production and productivity. To reduce the seroprevalence of this infectious agent, cows with a history of reproductive disorders should be tested, and new animals should be quarantined before being introduced into herds, and more research should be done to assess the impact of reproductive failure and other effects associated with this virus.