Microchannel fabrication on bio-grade Nitinol SMA byμ-ED milling process using sustainable oil for improving the machining performance and biocompatibility.

IF 8.2 2区 医学 Q1 ENGINEERING, BIOMEDICAL
Satish Chaurasia, Kishore Debnath
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引用次数: 0

Abstract

The process of micromachining has garnered attention for its ability to create three-dimensional tiny features, particularly in ultra-hard and exotic materials. The present work investigates the effect of different parameters of theμ-ED milling, such as pulse on time (Ton), pulse off time (Toff), voltage (V), and tool rotation (TR) on the dimensional deviation (DD), material removal rate (MRR), surface roughness (Ra), and machined surface characteristics (analyzed by EDS and FESEM). The sesame oil as dielectric and tungsten-copper as tool electrodes were used to maintain the accuracy and improve the machinability of bio-grade Nitinol shape memory alloy (SMA). Response surface methodology (RSM) and genetic algorithms (GAs) were used to optimize the various input parameters of theμ-ED milling process. Artificial neural network was combined with GA to find the best parametric combination for microchannel fabrication. The cytotoxicity test was also performed on the machined surface to analyze the biocompatibility of the machined surface. It was found that the cell viability of Nitinol SMA was improved by 85.11% after machining at the optimum condition. The highest MRR was found to be 0.076 gm min-1, and the lowest DD and Ra were found to be 16.47μm and Ra 0.387μm, respectively.

采用μ-ED铣削工艺制备生物级镍钛诺SMA微通道,提高加工性能和生物相容性。
微机械加工过程因其创造三维微小特征的能力而受到关注,特别是在超硬和奇异材料中。本研究研究了微ed铣削的不同参数,如脉冲开启时间(Ton)、脉冲关闭时间(Toff)、电压(V)和刀具旋转(TR)对尺寸偏差(DD)、材料去除率(MRR)、表面粗糙度(Ra)和加工表面特性(通过EDS和FESEM分析)的影响。以芝麻油为介质,钨铜为工具电极,保持生物级镍钛诺SMA的加工精度,提高其可加工性。采用响应面法(RSM)和遗传算法(GA)对微ed铣削工艺的各种输入参数进行了优化。将人工神经网络(ANN)与遗传算法相结合,寻找微通道加工的最佳参数组合。对加工表面进行细胞毒性试验,分析加工表面的生物相容性。结果表明,在最佳加工条件下,镍钛诺SMA的细胞活力提高了85.11%。最高MRR为0.076 gm/min,最低DD和Ra分别为16.47µm和0.387µm。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biofabrication
Biofabrication ENGINEERING, BIOMEDICAL-MATERIALS SCIENCE, BIOMATERIALS
CiteScore
17.40
自引率
3.30%
发文量
118
审稿时长
2 months
期刊介绍: Biofabrication is dedicated to advancing cutting-edge research on the utilization of cells, proteins, biological materials, and biomaterials as fundamental components for the construction of biological systems and/or therapeutic products. Additionally, it proudly serves as the official journal of the International Society for Biofabrication (ISBF).
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