Correlation between peripheral blood inflammatory markers and delayed cerebral ischemia after intracerebral hemorrhage.

IF 1.7 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
American journal of translational research Pub Date : 2024-12-15 eCollection Date: 2024-01-01 DOI:10.62347/ZXPV4184
Yuhua Wang, Aijun Liu, Fengju Hui, Ning Han, Wei Zhang, Yinzhou Sang
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引用次数: 0

Abstract

Objective: To assess the predictive value of peripheral blood inflammatory markers for delayed cerebral ischemia (DCI) in patients with intracerebral hemorrhage (ICH) and explore methods for early intervention.

Methods: This single-center retrospective study reviewed medical records of ICH patients admitted to Cangzhou People's Hospital over a 12-month period from January 2022 to December 2023. Of the 150 identified patients with ICH, including 80 patients without DCI (control group) and 70 with DCI (observation group). Demographics and blood biochemical markers during hospitalization were recorded. Binary logistic regression was used to identify independent factors influencing DCI occurrence.

Results: Significant differences were observed between the two groups in neutrophil percentage, lymphocyte percentage, lymphocytes absolute and neutrophil-to-lymphocyte ratio (NLR) (all P<0.05). Logistic regression analysis identified mRS score, lymphocyte percentage, educational level, uric acid, neutrophils percentage, and NLR as independent risk factors for DCI.

Conclusion: Neutrophil percentage and NLR are independent factors influencing delayed cerebral ischemia after intracerebral hemorrhage. These markers are readily accessible and may provide valuable insights for early ICH management.

外周血炎症标志物与脑出血后迟发性脑缺血的相关性研究。
目的:评价外周血炎症标志物对脑出血(ICH)患者迟发性脑缺血(DCI)的预测价值,探讨早期干预方法。方法:本研究为单中心回顾性研究,回顾了2022年1月至2023年12月沧州市人民医院收治的脑出血患者的病历。150例确诊脑出血患者中,无DCI患者80例(对照组),DCI患者70例(观察组)。记录住院期间的人口统计学和血液生化指标。采用二元逻辑回归确定影响DCI发生的独立因素。结果:两组间中性粒细胞百分比、淋巴细胞百分比、淋巴细胞绝对数、中性粒细胞/淋巴细胞比值(NLR)均有显著差异(均为p)。结论:中性粒细胞百分比和NLR是影响脑出血后迟发性脑缺血的独立因素。这些标记很容易获得,可能为早期ICH管理提供有价值的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
American journal of translational research
American journal of translational research ONCOLOGY-MEDICINE, RESEARCH & EXPERIMENTAL
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