Differentiation of intrapancreatic accessory spleen from pancreatic neuroendocrine tumor using MRI R2.

IF 2.3 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Abdominal Radiology Pub Date : 2025-01-22 DOI:10.1007/s00261-024-04758-y

Jun Gu Kang, Jae Hyon Park, Mi-Suk Park, Kyunghwa Han, Hee Seung Lee, Hyun Kyung Yang

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引用次数: 0

Abstract

Purpose: To evaluate the performance of R2* in distinguishing intrapancreatic accessory spleens (IPASs) from pancreatic neuroendocrine tumors (PNETs).

Methods: Two radiologists (R1 and R2) retrospectively reviewed the MRIs of 20 IPAS and 20 PNET patients. IPASs were diagnosed with uptake on 99mTc labeled heat-damaged red blood cell scintigraphy or characteristic findings on CT/MRI and ≥ 12 month-long-stability. PNETs were histopathologically diagnosed with resection. Using McNemar test, sensitivities and specificities of the diagnostic criterion based on R2* mass-to-spleen ratio (MSR) were compared with those of the other criteria using contrast-enhanced (CE) MRI and apparent diffusion coefficient (ADC) MSR.

Results: The study included 40 patients (median age, 54; interquartile range, 43-65; 24 men, 16 women). IPASs exhibited spleen-isointensity on T2WI, late arterial and portal phases, and diffusion-weighted images more frequently than PNETs (p <.05). ADC MSRs were lower (p <.001) and R2* MSRs were higher (p <.001) in IPASs compared to PNETs. For R1, sensitivity and specificity were 45.0% and 100.0% for criterion 1 (spleen-isointensity on CE-MRI); 45.0% and 85.0% for criterion 2 (ADC MSR ≤ 1.08); 90.0% and 95.0% for criterion 3 (0.9 ≤ R2* MSR ≤ 1.7). For R2, 75.0% and 100.0%; 45.0% and 90.0%; 90.0% and 100.0%. Criterion 3 showed higher sensitivity than criterion 1 for R1 (p =.004), and criterion 2 for R1 and R2 (p =.012). There was no difference in specificity.

Conclusion: For differentiating IPAS from PNET, R2* showed higher sensitivity than, and similar specificity to CE-MRI and ADC.

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胰腺内副脾与胰腺神经内分泌肿瘤的MRI R2鉴别。

目的：评价R2*在胰腺内副脾（IPASs）与胰腺神经内分泌肿瘤（PNETs）鉴别中的应用价值。方法：两位放射科医师（R1和R2）回顾性分析了20例IPAS和20例PNET患者的mri。IPASs诊断为99mTc标记热损伤红细胞显像摄取或CT/MRI特征性表现，且≥12个月的稳定性。PNETs经组织病理学诊断并切除。采用McNemar试验，比较R2*质脾比（MSR）诊断标准与其他对比增强（CE） MRI和表观扩散系数（ADC） MSR诊断标准的敏感性和特异性。结果：纳入40例患者(中位年龄54岁；四分位数范围43-65；男性24人，女性16人)。与PNETs相比，IPASs在T2WI、动脉晚期和门脉晚期、弥散加权图像上表现为脾脏等强度(p)。结论：R2*对IPAS与PNET的鉴别敏感性高于CE-MRI和ADC，特异性相似。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Abdominal Radiology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.20

自引率

8.30%

发文量

334

期刊介绍： Abdominal Radiology seeks to meet the professional needs of the abdominal radiologist by publishing clinically pertinent original, review and practice related articles on the gastrointestinal and genitourinary tracts and abdominal interventional and radiologic procedures. Case reports are generally not accepted unless they are the first report of a new disease or condition, or part of a special solicited section. Reasons to Publish Your Article in Abdominal Radiology: · Official journal of the Society of Abdominal Radiology (SAR) · Published in Cooperation with: European Society of Gastrointestinal and Abdominal Radiology (ESGAR) European Society of Urogenital Radiology (ESUR) Asian Society of Abdominal Radiology (ASAR) · Efficient handling and Expeditious review · Author feedback is provided in a mentoring style · Global readership · Readers can earn CME credits