Increase in serum parathyroid hormone level intraoperatively after parathyroidectomy for primary hyperparathyroidism

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

American Journal of Otolaryngology Pub Date : 2025-01-15 DOI:10.1016/j.amjoto.2025.104598

Bassam Abboud , Christopher Abboud

{"title":"Increase in serum parathyroid hormone level intraoperatively after parathyroidectomy for primary hyperparathyroidism","authors":"Bassam Abboud , Christopher Abboud","doi":"10.1016/j.amjoto.2025.104598","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>To evaluate the significance of increased of intraoperative parathyroid hormone(IOPTH) 10 min after parathyroidectomy in primary hyperparathyroidism.</div></div><div><h3>Methods</h3><div>All patients underwent parathyroidectomy were retrospectively included. Following the results of IOPTH, three groups were defined: Group 1: increased of IOPTH, Group 2: <50 % decreased of IOPTH, and Group 3: >50 % decreased of IOPTH.</div></div><div><h3>Results</h3><div>Unilateral approach was performed and shifted to bilateral neck exploration(BNE) when indicated. There were single adenoma, double adenomas, and hyperplasia in 84 %, 5 %, and 11 % of cases respectively. We noted that 100 %, 80 %, and 4 % of patients had a polyglandular diseases in Groups 1, 2, and 3 respectively. Double adenoma and hyperplasia were present in 55 %, and 45 %, 22 %, and 58 %, 1 %, and 3 % in Groups 1, 2, and 3 respectively. Female patients represented 55 %, 71 %, and 81 % of patients in Groups 1, 2, and 3 respectively. Cure rate was 99 %.</div></div><div><h3>Conclusions</h3><div>Patients with increased of IOPTH level 10 min after parathyroidectomy had a polyglandular diseases in 100 % of cases and needed BNE.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 2","pages":"Article 104598"},"PeriodicalIF":1.8000,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Otolaryngology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0196070925000018","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

To evaluate the significance of increased of intraoperative parathyroid hormone(IOPTH) 10 min after parathyroidectomy in primary hyperparathyroidism.

Methods

All patients underwent parathyroidectomy were retrospectively included. Following the results of IOPTH, three groups were defined: Group 1: increased of IOPTH, Group 2: <50 % decreased of IOPTH, and Group 3: >50 % decreased of IOPTH.

Results

Unilateral approach was performed and shifted to bilateral neck exploration(BNE) when indicated. There were single adenoma, double adenomas, and hyperplasia in 84 %, 5 %, and 11 % of cases respectively. We noted that 100 %, 80 %, and 4 % of patients had a polyglandular diseases in Groups 1, 2, and 3 respectively. Double adenoma and hyperplasia were present in 55 %, and 45 %, 22 %, and 58 %, 1 %, and 3 % in Groups 1, 2, and 3 respectively. Female patients represented 55 %, 71 %, and 81 % of patients in Groups 1, 2, and 3 respectively. Cure rate was 99 %.

Conclusions

Patients with increased of IOPTH level 10 min after parathyroidectomy had a polyglandular diseases in 100 % of cases and needed BNE.

查看原文本刊更多论文

原发性甲状旁腺功能亢进手术后血清甲状旁腺激素水平升高。

背景：探讨原发性甲状旁腺功能亢进患者在甲状旁腺切除术后10分钟术中甲状腺激素（IOPTH）升高的意义。方法：回顾性分析所有行甲状旁腺切除术的患者。根据IOPTH结果将大鼠分为三组：第一组IOPTH升高，第二组IOPTH降低50%。结果：采用单侧入路，并在需要时转向双侧颈部探查（BNE）。单发腺瘤、双发腺瘤和增生分别占84%、5%和11%。我们注意到，在第1、2和3组中，分别有100%、80%和4%的患者患有多腺疾病。在第1、2、3组中，双腺瘤和增生的发生率分别为55%、45%、22%、58%、1%和3%。在第1、2、3组中，女性患者分别占55%、71%和81%。治愈率为99%。结论：甲状旁腺切除术后10 min IOPTH水平升高的患者100%为多腺病变，需行BNE治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

American Journal of Otolaryngology 医学-耳鼻喉科学

CiteScore

4.40

自引率

4.00%

发文量

378

审稿时长

41 days

期刊介绍： Be fully informed about developments in otology, neurotology, audiology, rhinology, allergy, laryngology, speech science, bronchoesophagology, facial plastic surgery, and head and neck surgery. Featured sections include original contributions, grand rounds, current reviews, case reports and socioeconomics.