Leveraging eCAP thresholds in a logistic model to predict speech outcomes after implantation in anomalous cochlea.

IF 1.2 4区医学 Q3 OTORHINOLARYNGOLOGY

Acta Oto-Laryngologica Pub Date : 2025-01-16 DOI:10.1080/00016489.2024.2449251

Das K Nidhin, Amit Keshri, Ravisankar Manogaran, Nazrin Hameed, Prabhakar Mishra, Mohd Aqib, Kalyan Chidambaram, Mohit Sinha

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引用次数: 0

Abstract

Background: Pediatric cochlear implant (CI) recipients with cochlear malformations face challenges due to variable speech recognition outcomes.

Aims/objectives: This study assesses the predictive value of intraoperative electrically evoked compound action potential (eCAP) thresholds, residual hearing, age at implantation, Intelligent Quotient (IQ), and malformation type for speech recognition outcomes.

Material and methods: A prospective cohort of 52 children (aged 1-4 years) with cochlear malformations who underwent CI between 2016 and 2024 was analyzed. Intraoperative eCAP thresholds were recorded, and disyllable word recognition scores (WRS) were evaluated 24 months postoperatively.

Results: Patients included incomplete partition (IP-II, 46.2%), cochlear hypoplasia (30.8%), IP-I (13.5%), and common cavity (9.6%). IP-II cases had higher mean eCAP thresholds (18.85 µV) compared to cochlear hypoplasia and common cavity cases. Higher eCAP thresholds correlated with better WRS outcomes (p < 0.001). Logistic regression revealed eCAP thresholds, residual hearing, age, IQ, and malformation type as significant predictors, with an AUC of 0.92.

Conclusions and significance: Intraoperative eCAP thresholds and residual hearing strongly predict auditory outcomes in children with cochlear malformations. Tailored CI strategies based on individual profiles can optimize speech recognition outcomes.

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利用逻辑模型中的eCAP阈值预测异常耳蜗植入后的语音结果。

背景：患有耳蜗畸形的儿童人工耳蜗（CI）受者由于语音识别结果的变化而面临挑战。目的：本研究评估术中电诱发复合动作电位（eCAP）阈值、残余听力、植入年龄、智商（IQ）和畸形类型对语音识别结果的预测价值。材料和方法：对2016年至2024年间接受人工耳蜗手术的52名耳蜗畸形儿童（1-4岁）进行前瞻性队列分析。记录术中eCAP阈值，并评估术后24个月双音节词识别评分（WRS）。结果：患者包括IP-II型（46.2%）、耳蜗发育不全（30.8%）、IP-I型（13.5%）、共腔（9.6%）。与耳蜗发育不全和普通腔相比，IP-II患者的平均eCAP阈值（18.85µV）更高。结论和意义：术中eCAP阈值和残余听力能很好地预测耳蜗畸形患儿的听觉结局。基于个人配置文件的定制CI策略可以优化语音识别结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Oto-Laryngologica 医学-耳鼻喉科学

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

3-6 weeks

期刊介绍： Acta Oto-Laryngologica is a truly international journal for translational otolaryngology and head- and neck surgery. The journal presents cutting-edge papers on clinical practice, clinical research and basic sciences. Acta also bridges the gap between clinical and basic research.