{"title":"Two-fluid flow of blood in a curved stenotic artery under pulsating condition","authors":"Muhammad Shahzad Shabbir, Meriyem Hussain","doi":"10.1007/s10867-024-09668-0","DOIUrl":null,"url":null,"abstract":"<div><p>The present article focuses on the analysis of the two-phase flow of blood via a stenosed artery under the influence of a pulsatile pressure gradient. The core and plasma regions of flow are modeled using the constitutive relations of Herschel-Bulkley and the Newtonian fluids, respectively. The problem is modeled in a cylindrical coordinate system. A modest stenosis assumption is used to simplify the non-dimensional governing equations of the flow issue. An explicit finite difference approach is used to solve the resultant nonlinear system of differential equations while accounting for the provided boundary conditions. After the necessary adjustments have been made to the crucial non-dimensional parameters, an analysis of the data behind the huge image, such as axial velocity, temperature field, concentration wall shear stress, flow rate, and flow impedance, is conducted. The current study shows that the curvature of blood vessels plays a significant role in influencing blood velocity. Specifically, a unit increase in the curvature radius results in a 24% rise in blood velocity.</p></div>","PeriodicalId":612,"journal":{"name":"Journal of Biological Physics","volume":"51 1","pages":""},"PeriodicalIF":1.8000,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biological Physics","FirstCategoryId":"99","ListUrlMain":"https://link.springer.com/article/10.1007/s10867-024-09668-0","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOPHYSICS","Score":null,"Total":0}
引用次数: 0
Abstract
The present article focuses on the analysis of the two-phase flow of blood via a stenosed artery under the influence of a pulsatile pressure gradient. The core and plasma regions of flow are modeled using the constitutive relations of Herschel-Bulkley and the Newtonian fluids, respectively. The problem is modeled in a cylindrical coordinate system. A modest stenosis assumption is used to simplify the non-dimensional governing equations of the flow issue. An explicit finite difference approach is used to solve the resultant nonlinear system of differential equations while accounting for the provided boundary conditions. After the necessary adjustments have been made to the crucial non-dimensional parameters, an analysis of the data behind the huge image, such as axial velocity, temperature field, concentration wall shear stress, flow rate, and flow impedance, is conducted. The current study shows that the curvature of blood vessels plays a significant role in influencing blood velocity. Specifically, a unit increase in the curvature radius results in a 24% rise in blood velocity.
期刊介绍:
Many physicists are turning their attention to domains that were not traditionally part of physics and are applying the sophisticated tools of theoretical, computational and experimental physics to investigate biological processes, systems and materials.
The Journal of Biological Physics provides a medium where this growing community of scientists can publish its results and discuss its aims and methods. It welcomes papers which use the tools of physics in an innovative way to study biological problems, as well as research aimed at providing a better understanding of the physical principles underlying biological processes.