Eva Kozanli, Angelique M A M Winkel, Alvin X Han, Sharon van den Brink, Annemarie van den Brandt, Milly E Haverkort, Sjoerd Euser, Colin A Russell, Menno D de Jong, Marlies A van Houten, Steven F L van Lelyveld, Dirk Eggink
{"title":"Shortened SARS-CoV-2 viral RNA shedding in saliva during early Omicron compared to wild-type pandemic phase","authors":"Eva Kozanli, Angelique M A M Winkel, Alvin X Han, Sharon van den Brink, Annemarie van den Brandt, Milly E Haverkort, Sjoerd Euser, Colin A Russell, Menno D de Jong, Marlies A van Houten, Steven F L van Lelyveld, Dirk Eggink","doi":"10.1093/infdis/jiaf031","DOIUrl":null,"url":null,"abstract":"This study compared the dynamics of SARS-CoV-2 viral shedding in saliva between wild-type virus-infected and Omicron-infected household cohorts. Pre-existing immunity in participants likely shortens the viral RNA shedding duration and lowers viral load peaks. Frequent saliva sampling can be a convenient tool to study viral load dynamics.","PeriodicalId":501010,"journal":{"name":"The Journal of Infectious Diseases","volume":"60 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/infdis/jiaf031","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This study compared the dynamics of SARS-CoV-2 viral shedding in saliva between wild-type virus-infected and Omicron-infected household cohorts. Pre-existing immunity in participants likely shortens the viral RNA shedding duration and lowers viral load peaks. Frequent saliva sampling can be a convenient tool to study viral load dynamics.