[Thrombectomy : Stent retriever vs aspiration].

Radiologie (Heidelberg, Germany) Pub Date : 2025-02-01 Epub Date: 2025-01-15 DOI:10.1007/s00117-024-01406-w
Ruben Mühl-Benninghaus
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引用次数: 0

Abstract

Besides intravenous thrombolysis, endovascular therapy (EVT) is also a standard treatment option for acute ischemic stroke. The clinical efficacy and safety of this procedure was proven in 2015 by several randomized controlled trials. The aim of EVT is to achieve the fastest possible recanalization of an occluded artery supplying the brain and, thus, reperfusion of the brain tissue. In EVT, the thrombus is thrombectomized mechanically using wire-mounted self-expanding stents (so-called stent retrievers) and/or aspirated through aspiration catheters. The extent of brain tissue reperfusion influences the clinical outcome of the affected patients. High reperfusion scores (Thrombolysis in Cerebral Infarction [TICI]) correlate positively with more favorable clinical outcomes. However, even after achieving high TICI scores, the clinical outcome of stroke patients with large vessel occlusions varies considerably. There are many reasons for this. In addition to the collateral supply and the perfusion pressure of the affected brain area, the period of tissue ischemia plays a particularly important role in preservation of brain function. In addition to the TICI score, the number of thrombectomy maneuvers performed and consequently the duration of the intervention has an influence on the clinical outcome of the treated patients.

[取栓:支架取栓vs抽吸]。
除静脉溶栓外,血管内治疗(EVT)也是急性缺血性卒中的标准治疗方案。2015 年,多项随机对照试验证明了该疗法的临床疗效和安全性。EVT 的目的是以最快的速度再通闭塞的脑供血动脉,从而实现脑组织的再灌注。在EVT中,血栓是通过安装在导线上的自膨胀支架(即所谓的支架取栓器)和/或通过抽吸导管进行机械切除的。脑组织再灌注的程度影响患者的临床预后。高再灌注评分(脑梗塞溶栓治疗评分[TICI])与更有利的临床预后呈正相关。然而,即使获得了较高的 TICI 分数,大血管闭塞的卒中患者的临床预后仍有很大差异。造成这种情况的原因有很多。除了侧支供应和受影响脑区的灌注压力外,组织缺血期对脑功能的保护也起着特别重要的作用。除 TICI 评分外,进行血栓切除操作的次数以及干预的持续时间也会对治疗患者的临床结果产生影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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