Mayank A Nanavaty, Margarita Safir, Laura McLaughlin, Joy White
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引用次数: 0
Abstract
Purpose: To assess the relationship between angle kappa (apparent chord mu) and ocular parameters in cataract patients.
Methods: In this cross-sectional study, the data on apparent chord mu, age, axial length, anterior chamber depth, anterior and posterior mean keratometry, mean total keratometry, white-to-white, central corneal thickness and lens thickness were collected for consecutive cataract patients. Correlation (Pearson) between chord mu and the other ocular parameters was calculated. A stepwise backward multiple regression analysis was performed to identify the combination of ocular parameters strongly correlating to chord mu.
Results: Two thousand four hundred and sixty-four eyes (1232 patients) were included in this study. The mean age was 72.7 ± 12.7 years (18-97 years). Univariate analysis showed a significant positive correlation of chord mu to age (R = 0.06, p = .01), lens thickness (R = 0.12, p < .01), mean keratometry (R = 0.08, p < .01), and mean total keratometry (R = 0.08, p < .01). Whereas there was a significant negative correlation with white-to-white (R = -0.04, p = .03), axial length (R = -0.19, p < .01), and anterior chamber depth (R = -0.2, p < .01). Male gender (R = -0.04, p = .05) and central corneal thickness (R = 0.04, p = .06) were not significantly correlated. Multivariate stepwise backward regression analysis showed a combination of four factors (female sex, reduced axial length and anterior chamber depth and steep mean keratometry) significantly related to chord mu (angle kappa).
Conclusion: Female gender, reduced axial length and anterior chamber depth, and higher mean keratometry correlate to apparent chord mu (angle kappa) in cataract patients. These findings can help identify vulnerable patients who can have appropriate counseling on the prognosis of postoperative optical and visual outcomes.
目的:探讨白内障患者视弦角kappa(视弦mu)与眼参数的关系。方法:采用横断面研究方法,收集连续白内障患者的视弦mu、年龄、眼轴长度、前房深度、前后平均角膜密度、平均总角膜密度、白对白、角膜中央厚度、晶状体厚度等资料。计算弦mu与其他眼参数的相关性(Pearson)。采用逐步反向多元回归分析,确定与弦mu密切相关的眼参数组合。结果:本研究纳入2464只眼(1232例)。平均年龄72.7±12.7岁(18-97岁)。单因素分析显示,弦mu与年龄(R = 0.06, p = 0.01)、晶状体厚度(R = 0.12, p R = 0.08, p R = 0.08, p R = -0.04, p = 0.03)、眼轴长度(R = -0.19, p R = -0.2, p R = -0.04, p = 0.05)、角膜中央厚度(R = 0.04, p = 0.06)无显著相关。多元逐步回归分析显示,女性性别、前房轴长、前房深度减小、平均角膜曲率陡等4个因素与弦mu(角kappa)显著相关。结论:女性、眼轴长度和前房深度减小、平均角膜度数增高与白内障患者视弦mu(角kappa)相关。这些发现可以帮助识别易受伤害的患者,他们可以对术后视力预后进行适当的咨询。
期刊介绍:
The principal aim of Current Eye Research is to provide rapid publication of full papers, short communications and mini-reviews, all high quality. Current Eye Research publishes articles encompassing all the areas of eye research. Subject areas include the following: clinical research, anatomy, physiology, biophysics, biochemistry, pharmacology, developmental biology, microbiology and immunology.