Association between body mass index at birth and neonatal health outcomes in preterm infants: A retrospective analysis.

IF 2.7 3区医学 Q1 PEDIATRICS

Pediatric Obesity Pub Date : 2025-01-14 DOI:10.1111/ijpo.13203

Chuntian Liu, Yijia Chen, Mengqing Pan, Xiaoyu Lu, Jianhong Xu, Xiaochun Chen

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引用次数: 0

Abstract

Background: Studies on how birth body mass index (BMI) affects health outcomes in preterm infants are relatively limited.

Aim: To analyze the association between BMI at birth and neonatal health outcomes in extremely low and very low birth weight preterm infants in China.

Methods: Used data from the Chinese Premature Infant Informatization Platform (2022-2023). Preterm infants were categorized based on their birth BMI z-scores into three groups: low BMI group (< -2), normal BMI group (-2 to 2) and high BMI group (>2). The relationship between BMI and neonatal health outcomes was then analyzed.

Results: The final analysis included 1662 extremely low and very low birth weight preterm infants. The results indicated that low BMI was significantly associated with an increased risk of respiratory distress syndrome (RDS) (AOR 1.61, 95% CI 1.31-2.30), bronchopulmonary dysplasia (BPD) (AOR 1.34, 95% CI 1.00-1.80) and necrotizing enterocolitis (NEC) (AOR 1.57, 95% CI 1.01-2.42). High BMI was significantly associated with an increased risk of RDS (AOR 1.60, 95% CI 1.05-2.45).

Conclusions: BMI at birth is significantly associated with the risks of RDS, BPD and NEC in ELBW and VLBW, highlighting the importance of monitoring BMI as an additional risk predictor in a population of neonates already at high risk for adverse outcomes.

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早产儿出生时体重指数与新生儿健康结局的关系：一项回顾性分析

背景：关于出生体重指数（BMI）如何影响早产儿健康结局的研究相对有限。目的：分析中国极低和极低出生体重早产儿出生时体重指数与新生儿健康结局的关系。方法：使用中国早产儿信息化平台（2022-2023）数据。根据早产儿出生时BMI z-score分为3组：低BMI组（< -2）、正常BMI组（-2 ~ 2）和高BMI组（bb0 2）。然后分析BMI与新生儿健康结局之间的关系。结果：最终分析了1662例极低和极低出生体重早产儿。结果显示，低BMI与呼吸窘迫综合征（RDS）（AOR 1.61, 95% CI 1.31-2.30）、支气管肺发育不良（BPD）（AOR 1.34, 95% CI 1.00-1.80）和坏死性小肠结肠炎（NEC）（AOR 1.57, 95% CI 1.01-2.42）的风险增加显著相关。高BMI与RDS风险增加显著相关（AOR 1.60, 95% CI 1.05-2.45）。结论：出生时的BMI与ELBW和VLBW中RDS、BPD和NEC的风险显著相关，强调了在已经处于不良结局高风险的新生儿群体中监测BMI作为额外风险预测因子的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Obesity PEDIATRICS-

CiteScore

7.30

自引率

5.30%

发文量

117

审稿时长

6-12 weeks

期刊介绍： Pediatric Obesity is a peer-reviewed, monthly journal devoted to research into obesity during childhood and adolescence. The topic is currently at the centre of intense interest in the scientific community, and is of increasing concern to health policy-makers and the public at large. Pediatric Obesity has established itself as the leading journal for high quality papers in this field, including, but not limited to, the following: Genetic, molecular, biochemical and physiological aspects of obesity – basic, applied and clinical studies relating to mechanisms of the development of obesity throughout the life course and the consequent effects of obesity on health outcomes Metabolic consequences of child and adolescent obesity Epidemiological and population-based studies of child and adolescent overweight and obesity Measurement and diagnostic issues in assessing child and adolescent adiposity, physical activity and nutrition Clinical management of children and adolescents with obesity including studies of treatment and prevention Co-morbidities linked to child and adolescent obesity – mechanisms, assessment, and treatment Life-cycle factors eg familial, intrauterine and developmental aspects of child and adolescent obesity Nutrition security and the "double burden" of obesity and malnutrition Health promotion strategies around the issues of obesity, nutrition and physical activity in children and adolescents Community and public health measures to prevent overweight and obesity in children and adolescents.