{"title":"Developmental Venous Anomaly: Its Impact on Brain Parenchymal Function as Revealed by FDG PET.","authors":"Pei Ing Ngam, Yoshimi Anzai, Satoshi Minoshima","doi":"10.1097/RLU.0000000000005654","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Developmental venous anomaly (DVA) is a common benign brain vascular malformation, typically asymptomatic, with intervention required when complications arise. We present the case of a 63-year-old man with mild cognitive decline whose brain FDG PET showed decreased uptake not only at the site of DVA, but in the extended surrounding parenchyma where MRI showed no parenchymal abnormalities. DVAs arise from developmental irregularities in the embryonic venous system, but likely affecting a greater extent of the surrounding parenchymal functions. These findings highlight the clinical significance of DVAs and their effects on the parenchymal function seen on FDG PET albeit normal parenchyma on structural imaging.</p>","PeriodicalId":10692,"journal":{"name":"Clinical Nuclear Medicine","volume":" ","pages":"360-361"},"PeriodicalIF":9.6000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Nuclear Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/RLU.0000000000005654","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/14 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: Developmental venous anomaly (DVA) is a common benign brain vascular malformation, typically asymptomatic, with intervention required when complications arise. We present the case of a 63-year-old man with mild cognitive decline whose brain FDG PET showed decreased uptake not only at the site of DVA, but in the extended surrounding parenchyma where MRI showed no parenchymal abnormalities. DVAs arise from developmental irregularities in the embryonic venous system, but likely affecting a greater extent of the surrounding parenchymal functions. These findings highlight the clinical significance of DVAs and their effects on the parenchymal function seen on FDG PET albeit normal parenchyma on structural imaging.
摘要:发育性静脉异常(DVA)是一种常见的良性脑血管畸形,通常无症状,当出现并发症时才需要干预。我们介绍了一例 63 岁的轻度认知功能减退的男性病例,其脑 FDG PET 不仅在 DVA 的部位显示摄取减少,而且在核磁共振成像未显示实质异常的扩展周围实质中也显示摄取减少。DVA源于胚胎静脉系统的发育异常,但很可能会影响周围更大程度的实质功能。这些发现凸显了 DVA 的临床意义及其对 FDG PET 显示的实质功能的影响,尽管结构成像显示实质正常。
期刊介绍:
Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty.
Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.