Electronic structure modulation of ultrathin PtRuMoCoNi high-entropy alloy nanowires for boosting peroxidase-like activity and sensitive colorimetric determination of isoniazid and hydrazine
{"title":"Electronic structure modulation of ultrathin PtRuMoCoNi high-entropy alloy nanowires for boosting peroxidase-like activity and sensitive colorimetric determination of isoniazid and hydrazine","authors":"Jia-Qi Li, Ai-Jun Wang, Pei Song, Jiu-Ju Feng, Qi Zhou, Tuck Yun Cheang","doi":"10.1007/s00604-024-06892-2","DOIUrl":null,"url":null,"abstract":"<div><p>Self-supported ultrathin PtRuMoCoNi high-entropy alloy nanowires (HEANWs) were synthesized by a one-pot co-reduction method, whose peroxidase (POD)-like activity and catalytic mechanism were elaborated in detail. As expected, the PtRuMoCoNi HEANWs showed excellent POD-like activity. It can quickly catalyze the oxidization of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) to blue <sub>OX</sub>TMB through decomposition of H<sub>2</sub>O<sub>2</sub> to superoxide radicals. Notably, isoniazid and hydrazine effectively scavenge the as-produced superoxide radicals and reduce the blue <sub>OX</sub>TMB, showing high reduction ability and antioxidant property. Thus, the PtRuMoCoNi HEANW-derived colorimetric method was developed for determination of isoniazid and hydrazine, which exhibited the linear ranges of 1.5 to 50 μM and 25 to 200 μM coupled with the lower detection limits of 2.3 and 12.6 μM for isoniazid and hydrazine, respectively. The excellent analytical performance mainly results from the synergistic catalytic effect of the multiple metals and distinctive ultra-thin nanowires. This work provides a simple and rapid colorimetric method for the determination of isoniazid and hydrazine in actual samples.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 2","pages":""},"PeriodicalIF":5.3000,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchimica Acta","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s00604-024-06892-2","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Self-supported ultrathin PtRuMoCoNi high-entropy alloy nanowires (HEANWs) were synthesized by a one-pot co-reduction method, whose peroxidase (POD)-like activity and catalytic mechanism were elaborated in detail. As expected, the PtRuMoCoNi HEANWs showed excellent POD-like activity. It can quickly catalyze the oxidization of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) to blue OXTMB through decomposition of H2O2 to superoxide radicals. Notably, isoniazid and hydrazine effectively scavenge the as-produced superoxide radicals and reduce the blue OXTMB, showing high reduction ability and antioxidant property. Thus, the PtRuMoCoNi HEANW-derived colorimetric method was developed for determination of isoniazid and hydrazine, which exhibited the linear ranges of 1.5 to 50 μM and 25 to 200 μM coupled with the lower detection limits of 2.3 and 12.6 μM for isoniazid and hydrazine, respectively. The excellent analytical performance mainly results from the synergistic catalytic effect of the multiple metals and distinctive ultra-thin nanowires. This work provides a simple and rapid colorimetric method for the determination of isoniazid and hydrazine in actual samples.
期刊介绍:
As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.