Study of the iodine-promoted cyclization of 4,5-diethynyl-1,2,3-triazoles for the synthesis of triazole-iodoheterocyclic dyads

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2025-01-14 DOI:10.1007/s11172-024-4447-8

A. I. Govdi, K. V. Kimele, I. A. Balova

引用次数: 0

Abstract

A series of functionalized 4,5-bis(arylethynyl)triazoles were prepared by a copper-catalyzed cycloaddition of 1-iodobuta-1,3-diynes and azides and subsequent Sonogashira reaction of iodoethynyltriazoles with substituted arylacetylenes. The iodine-promoted cyclization of 4,5-bis(arylethynyl)triazoles involved only one triple bond and led to the formation of 2-triazolyl-3-iodoheteroindenes or 5-(4-iodoisochromeno)triazoles.

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碘促进4,5-二乙基-1,2,3-三唑环化合成三唑-碘杂环二偶体的研究

通过铜催化1-碘丁-1,3-二炔和叠氮化物的环加成和碘乙基三唑与取代芳基乙炔的Sonogashira反应，制备了一系列功能化的4,5-双（芳基乙基）三唑。碘促进4,5-二（芳基乙基）三唑的环化只涉及一个三键，并形成2-三唑-3-碘杂吲哚或5-（4-碘异色）三唑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.