Interleukin-17 and fat: Timing is everything

IF 25.5 1区医学 Q1 IMMUNOLOGY

Immunity Pub Date : 2025-01-14 DOI:10.1016/j.immuni.2024.12.005

Matthew C. Sinton, Olivia Shorthouse, Alice Costain, Juan F. Quintana

引用次数: 0

Abstract

Interleukin-17 plays a major role in controlling adipose tissue homeostasis. In a recent study published in Nature, Douglas et al. demonstrate that time-of-day-dependent expression of interleukin-17 by tissue-resident innate lymphocytes in the adipose tissue drives circadian regulation of adipose tissue homeostasis and function.

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白细胞介素-17 在控制脂肪组织平衡方面发挥着重要作用。道格拉斯等人最近在《自然》（Nature）杂志上发表的一项研究表明，脂肪组织中的组织驻留先天性淋巴细胞表达的白细胞介素-17具有时间-日依赖性，可驱动脂肪组织平衡和功能的昼夜节律调节。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Immunity 医学-免疫学

CiteScore

49.40

自引率

2.20%

发文量

205

审稿时长

6 months

期刊介绍： Immunity is a publication that focuses on publishing significant advancements in research related to immunology. We encourage the submission of studies that offer groundbreaking immunological discoveries, whether at the molecular, cellular, or whole organism level. Topics of interest encompass a wide range, such as cancer, infectious diseases, neuroimmunology, autoimmune diseases, allergies, mucosal immunity, metabolic diseases, and homeostasis.