Jinxing Shi, Zhongxin Kong, Jinkun Zhong, Xiaoqiu Zhang, Xianmin Luo, Heyu Wang, Boyang Xu, Xin Wang, Rui Cheng, Yang Yuan, Na Li, Quan Xie, Guoqiang Li, Haiyan Jia, Zhengqiang Ma
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引用次数: 0
Abstract
Ambiguity about whether the histidine-rich calcium-binding protein-coding gene (HisR) or the pore-forming toxin-like gene (PFT) or both are responsible for Fusarium head blight (FHB) resistance conferred by the Fhb1 quantitative trait locus hinders progress toward elucidating Fhb1 resistance mechanisms. Here, with a series of developed lines with or without PFT but all possessing HisR and five HisR-carrying PFT mutant lines created via gene editing, we show that PFT does not confer FHB resistance and that the HisR resistance effect does not require PFT in the tested conditions. We also show that PFT mutations are not associated with morphological and phenological characteristics that often affect FHB severity.
期刊介绍：
Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human and plant traits and on other model organisms. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation.
Integrative genetic topics comprise, but are not limited to:
-Genes in the pathology of human disease
-Molecular analysis of simple and complex genetic traits
-Cancer genetics
-Agricultural genomics
-Developmental genetics
-Regulatory variation in gene expression
-Strategies and technologies for extracting function from genomic data
-Pharmacological genomics
-Genome evolution
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