Evaluation of five questionnaires for obstructive sleep apnea screening in the elderly.

IF 3.9 2区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Scientific Reports Pub Date : 2025-01-11 DOI:10.1038/s41598-025-86041-8

Riken Chen, Jinru Zhu, Yitian Yang, Weifeng Liao, Weilong Ye, Lianfang Du, Mingdi Chen, Yuan Zhang, Weimin Yao, Zhenzhen Zheng

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Abstract

Obstructive sleep apnea (OSA) often leads to complications in the elderly. This study compares the usefulness of five screening tools for OSA in elderly patients. Data from elderly patients diagnosed with OSA, collected from the Sleep Medicine Center of the First Affiliated Hospital of Guangzhou Medical University from January 2012 to June 2017, is analyzed. The sensitivity, specificity, predictive values, area under the curve (AUC), and diagnostic odds ratio (DOR) of the five screening tools are computed and compared. 273 elderly patients with suspected OSA are included, of whom 189 are male (69.2%). The Berlin Questionnaire has an AUC of 0.670 (95%CI: 0.611-0.725) at different cut-off points. The sensitivity and specificity of the Berlin Questionnaire are noticeably high at 0.653 (0.587-0.719) and 0.608 (0.497-0.719), 0.699 (0.621-0.776) and 0.533 (0.449-0.616), and 0.803 (0.713-0.892) and 0.503 (0.433-0.572) when the AHI is 5, 15, and 30 times/hour, respectively. The GOAL Questionnaire has the highest DOR at AHI cut-off points of 5 and 15 times/hour, while Berlin has the highest DOR at an AHI cut-off point of 30 times/hour. Comprehensive use of these five screening questionnaires for suspected OSA in elderly patients aged 60 years and older is valuable and worth promoting among the elderly population.

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老年人阻塞性睡眠呼吸暂停筛查5份问卷的评价。

阻塞性睡眠呼吸暂停（OSA）常导致老年人并发症。本研究比较了五种筛查工具对老年OSA患者的有用性。对2012年1月至2017年6月广州医科大学第一附属医院睡眠医学中心诊断为OSA的老年患者的数据进行分析。计算并比较5种筛查工具的敏感性、特异性、预测值、曲线下面积（AUC）和诊断优势比（DOR）。纳入疑似OSA的老年患者273例，其中男性189例（69.2%）。柏林问卷在不同分界点上的AUC为0.670 （95%CI: 0.611-0.725）。当AHI为5次/小时、15次/小时、30次/小时时，柏林问卷的灵敏度和特异度分别为0.653（0.587-0.719）、0.608（0.497-0.719）、0.699（0.621-0.776）、0.533（0.449-0.616）和0.803（0.713-0.892）、0.503（0.433-0.572）。GOAL问卷在AHI分界点处DOR最高，分别为5次和15次/小时，而柏林在AHI分界点处DOR最高，为30次/小时。在60岁及以上的老年患者中综合使用这5份筛查问卷对疑似OSA有一定的价值，值得在老年人群中推广。

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来源期刊

Scientific Reports Natural Science Disciplines-

CiteScore

7.50

自引率

4.30%

发文量

19567

审稿时长

3.9 months

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