The Efficacy and Safety of Synchronized Radiofrequency and High Intensity Facial Electrical Stimulation in Improving Facial Skin Laxity and Quality in Asians

IF 2.2 3区医学 Q2 DERMATOLOGY

Lasers in Surgery and Medicine Pub Date : 2025-01-12 DOI:10.1002/lsm.23878

Woraphong Manuskiatti, Teerapat Wannawittayapa, Panyapat Buranaporn, Rungsima Wanitphadeedecha, Felix Paolo J. Lizarondo, Yanin Nokdhes

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引用次数: 0

Abstract

Background

Noninvasive aesthetic procedures for facial rejuvenation are gaining popularity. Conventional treatments, such as radiofrequency (RF) and high-intensity focused ultrasound (HIFU), primarily improve skin quality but do not address the deeper musculoaponeurotic structures that affect facial laxity. A novel approach that delivers synchronized RF with high intensity facial electrical stimulation (HIFES) thought to target both the skin and underlying musculoaponeurotic framework to effectively enhance facial laxity has been investigated.

Objective

To assess the long-term efficacy and safety of combined synchronous RF and HIFES therapies in treating facial skin laxity among Asian subjects.

Methods

In this prospective, evaluator-blinded study, 15 participants aged 40–65 years with mild to moderate facial skin laxity were enrolled. Each underwent four weekly treatments using a synchronized RF and HIFES system using noninvasive electrode applicators on the forehead and cheeks. Objective assessments included forehead and cheek lifting measurements using a 3D photographic system, eyebrow lifting measurement using ImageJ software, skin texture and melanin levels using Antera 3D®, and skin elasticity using Cutometer® MPA 580. Additionally, patients provided self-assessments regarding their perceived level of improvement. Assessments were conducted at baseline, before the 3rd treatment, and at 1 month, 3 months, and 6 months after the last treatment.

Results

All participants completed the study. Significant improvements were observed in forehead and cheek lifting sustained at 6 months (p < 0.0001). A significant eyebrow lift of 1.39 mm was observed at 3 months (p = 0.0087), with a sustained lifting distance of 1.31 mm at 6 months (p = 0.0021). Skin firmness improved substantially (p < 0.0001), with R0 (skin firmness) increasing by 81.24% at 6 months. Skin texture improved notably in the crow's feet area (13.82% improvement at 3 months, p = 0.049). Melanin levels decreased significantly in the crow's feet and forehead regions. Treatment was well tolerated, with pain scores decreasing from 3.5 ± 1.8 to 1.6  ± 1.0 by the fourth session. No serious adverse events occurred.

Conclusions

Combined synchronous RF and HIFES therapy is a safe and effective Noninvasive method of improving facial skin laxity and quality in Asian subjects. Lasers Surg. Med. 00:00–00, 2024. © 2024 Wiley Periodicals LLC.

Abstract Image

查看原文本刊更多论文

同步射频和高强度面部电刺激改善亚洲人面部皮肤松弛和质量的有效性和安全性。

背景：用于面部年轻化的无创美容手术越来越受欢迎。射频（RF）和高强度聚焦超声（HIFU）等传统治疗方法主要改善皮肤质量，但不能解决影响面部松弛的深层肌肉神经结构。研究人员采用了一种新方法，即同步射频和高强度面部电刺激（HIFES），这种方法被认为可同时针对皮肤和深层肌肉神经结构，从而有效改善面部松弛：评估同步射频和高强度面部电刺激疗法联合治疗亚洲受试者面部皮肤松弛的长期疗效和安全性：在这项前瞻性、评估者盲法研究中，共招募了 15 名年龄在 40-65 岁之间、患有轻度至中度面部皮肤松弛的受试者。每人每周接受四次治疗，使用同步射频和 HIFES 系统，在前额和脸颊使用非侵入性电极涂抹器。客观评估包括使用三维摄影系统测量前额和脸颊的提拉效果、使用 ImageJ 软件测量眉毛的提拉效果、使用 Antera 3D® 测量皮肤纹理和黑色素水平，以及使用 Cutometer® MPA 580 测量皮肤弹性。此外，患者还就其认为的改善程度进行了自我评估。评估在基线、第 3 次治疗前、最后一次治疗后 1 个月、3 个月和 6 个月进行：所有参与者都完成了研究。结果：所有参与者都完成了研究，额头和脸颊的提升效果在 6 个月后仍有明显改善（p 结论：额头和脸颊的提升效果在 6 个月后仍有明显改善：结合同步射频和 HIFES 疗法是一种安全有效的非侵入性方法，可改善亚洲受试者面部皮肤松弛和质量。Lasers Surg.Med.00:00-00, 2024.© 2024 Wiley Periodicals LLC.

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来源期刊

Lasers in Surgery and Medicine 医学-外科

CiteScore

5.40

自引率

12.50%

发文量

119

审稿时长

1 months

期刊介绍： Lasers in Surgery and Medicine publishes the highest quality research and clinical manuscripts in areas relating to the use of lasers in medicine and biology. The journal publishes basic and clinical studies on the therapeutic and diagnostic use of lasers in all the surgical and medical specialties. Contributions regarding clinical trials, new therapeutic techniques or instrumentation, laser biophysics and bioengineering, photobiology and photochemistry, outcomes research, cost-effectiveness, and other aspects of biomedicine are welcome. Using a process of rigorous yet rapid review of submitted manuscripts, findings of high scientific and medical interest are published with a minimum delay.