The First Case of Candida auris Detection and Infection Control in a Pediatric Bone Marrow Transplant Child Patient in Guangxi, China.

IF 2.9 3区 医学 Q2 INFECTIOUS DISEASES
Infection and Drug Resistance Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI:10.2147/IDR.S490696
Liu Yang, Kaiting Hong, Jiajia Luo, Lili Wang, Lei Zhang, Lijun Jiang, Qiliu Peng, Jian Guo
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引用次数: 0

Abstract

Candida auris is an emerging yeast species and an opportunistic pathogen. Due to its multi-drug resistance and ability to colonize and transmit, it poses a significant risk for outbreaks in medical institutions. In this study, we report the first case of C. auris detected in a pediatric bone marrow transplant child patient in Guangxi, China. C. auris was isolated from urine and identified using matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry, and the isolate belonged to clade I using sequencing. We have implemented stringent infection control measures including personal protective equipment and treatment in a single room, and conducted regular surveillance screening of patients' body surfaces, as well as those of related medical and logistics personnel, medical equipment, and surrounding environmental surfaces. These measures aim to effectively control the colonization of C. auris in patients, prevent its spread within hospitals, and ensure the quality of diagnosis and treatment for patients.

广西首例小儿骨髓移植患者耳念珠菌检测及感染控制。
耳念珠菌是一种新兴的酵母菌,是一种机会致病菌。由于其多重耐药性以及定植和传播能力,它对医疗机构的爆发构成了重大风险。在这项研究中,我们报告了在中国广西的一名儿童骨髓移植患者中发现的第一例耳念珠菌。采用基质辅助激光解吸电离飞行时间(MALDI-TOF)质谱法对尿中金黄色葡萄球菌(C. auris)进行了分离鉴定,经测序,该分离物属于I枝。我们严格执行个人防护装备、单间治疗等感染控制措施,定期对患者体表、相关医疗后勤人员体表、医疗设备、周边环境表面进行监测筛查。这些措施的目的是有效地控制患者c .耳的殖民化,防止医院内传播,并确保对患者诊断和治疗的质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Infection and Drug Resistance
Infection and Drug Resistance Medicine-Pharmacology (medical)
CiteScore
5.60
自引率
7.70%
发文量
826
审稿时长
16 weeks
期刊介绍: About Journal Editors Peer Reviewers Articles Article Publishing Charges Aims and Scope Call For Papers ISSN: 1178-6973 Editor-in-Chief: Professor Suresh Antony An international, peer-reviewed, open access journal that focuses on the optimal treatment of infection (bacterial, fungal and viral) and the development and institution of preventative strategies to minimize the development and spread of resistance.
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