Current trends and future directions in probiotics research for HIV/AIDS.

IF 4 2区生物学 Q2 MICROBIOLOGY

Frontiers in Microbiology Pub Date : 2024-12-27 eCollection Date: 2024-01-01 DOI:10.3389/fmicb.2024.1444552

Xinxin Cui, Zhanpeng Xie, Zhen Wu, Li-Qin Xu

{"title":"Current trends and future directions in probiotics research for HIV/AIDS.","authors":"Xinxin Cui, Zhanpeng Xie, Zhen Wu, Li-Qin Xu","doi":"10.3389/fmicb.2024.1444552","DOIUrl":null,"url":null,"abstract":"Aim: This study aims to comprehensively and systematically review the current status of research on probiotics and HIV/AIDS, while also exploring future research hotspots and trends in this domain.Methods: The Web of Science (WoS) Core Collection database was queried up until May 13, 2024, to retrieve relevant literature on probiotics and HIV/AIDS. Utilizing CiteSpace, VOSviewers, and Bibliometrix software, scientific achievements and research frontiers in this field were analyzed.Results: As of May 14, 2024, a total of 90 articles was included in. The publication output in this area peaked in 2017, with a subsequent decline in the number of articles post-2019. The United States emerged as the leading country in terms of article count (32 articles), with The University of Western Ontario being the institution with the highest publication output. Dr. Reid G contributed the most articles (12 articles). In addition to key terms, high-frequency keywords included immune activation, inflammation, and microbial translocation. The burst analysis of keywords suggests that vaccines may become a focal point of future research.Conclusion: Future research hotspots and trends should focus on elucidating the types of probiotics, intervention timing, and optimal strains (in terms of mixing ratios) in the context of HIV/AIDS. Furthermore, exploration into the role of probiotic metabolites, such as short-chain fatty acids, in vaccine development is warranted.","PeriodicalId":12466,"journal":{"name":"Frontiers in Microbiology","volume":"15 ","pages":"1444552"},"PeriodicalIF":4.0000,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11718315/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Microbiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.3389/fmicb.2024.1444552","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MICROBIOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Aim: This study aims to comprehensively and systematically review the current status of research on probiotics and HIV/AIDS, while also exploring future research hotspots and trends in this domain.

Methods: The Web of Science (WoS) Core Collection database was queried up until May 13, 2024, to retrieve relevant literature on probiotics and HIV/AIDS. Utilizing CiteSpace, VOSviewers, and Bibliometrix software, scientific achievements and research frontiers in this field were analyzed.

Results: As of May 14, 2024, a total of 90 articles was included in. The publication output in this area peaked in 2017, with a subsequent decline in the number of articles post-2019. The United States emerged as the leading country in terms of article count (32 articles), with The University of Western Ontario being the institution with the highest publication output. Dr. Reid G contributed the most articles (12 articles). In addition to key terms, high-frequency keywords included immune activation, inflammation, and microbial translocation. The burst analysis of keywords suggests that vaccines may become a focal point of future research.

Conclusion: Future research hotspots and trends should focus on elucidating the types of probiotics, intervention timing, and optimal strains (in terms of mixing ratios) in the context of HIV/AIDS. Furthermore, exploration into the role of probiotic metabolites, such as short-chain fatty acids, in vaccine development is warranted.

查看原文本刊更多论文

目的：本研究旨在全面系统地回顾益生菌与艾滋病的研究现状，同时探讨该领域未来的研究热点和趋势：方法：查询截至 2024 年 5 月 13 日的 Web of Science（WoS）核心数据库，检索有关益生菌与艾滋病的相关文献。利用 CiteSpace、VOSviewers 和 Bibliometrix 软件分析了该领域的科学成就和研究前沿：截至 2024 年 5 月 14 日，共收录了 90 篇文章。该领域的论文产出在2017年达到顶峰，2019年后论文数量随之下降。美国成为文章数量最多的国家（32 篇），而西安大略大学是发表文章最多的机构。Reid G 博士发表的文章最多（12 篇）。除关键词外，高频关键词还包括免疫激活、炎症和微生物转位。关键词的突发性分析表明，疫苗可能成为未来研究的焦点：结论：未来的研究热点和趋势应集中在阐明益生菌的类型、干预时机以及艾滋病毒/艾滋病情况下的最佳菌株（混合比例）。此外，还需要探索益生菌代谢产物（如短链脂肪酸）在疫苗开发中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Frontiers in Microbiology MICROBIOLOGY-

CiteScore

7.70

自引率

9.60%

发文量

4837

审稿时长

14 weeks

期刊介绍： Frontiers in Microbiology is a leading journal in its field, publishing rigorously peer-reviewed research across the entire spectrum of microbiology. Field Chief Editor Martin G. Klotz at Washington State University is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.