The 'MOAHLFA(P) Index': An Attempt to Standardise a Widely Used Array of Descriptors of Patch-Tested Patients.

IF 4.8 1区医学 Q2 ALLERGY

Contact Dermatitis Pub Date : 2025-01-12 DOI:10.1111/cod.14750

Wolfgang Uter, Klaus Ejner Andersen, Richard Brans, Magnus Bruze, Steffen Schubert, Margarida Gonçalo

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引用次数: 0

Abstract

Background: Since its inception in 1980, the MOHL index (% patients who are male, have occupational, hand, or leg dermatitis, respectively) and its later evolutions until the presently used MOAHLFA(P) index (adding % patients with atopic dermatitis, face dermatitis, age 40+ years and positive reaction(s) to ≥ 1 baseline series allergen) have been intended to convey important demographic and clinical information on the patients patch tested in a certain area and time, aiding the interpretation of the observed spectrum of sensitisation.

Objectives: To examine the current usage of the MOAHLFA(P) index and suggest consolidated definitions for its single items.

Methods: A title/abstract search in Medline identified publications mentioning the evolving acronyms. A Delphi-like survey among contact dermatitis experts collected agreement with suggested definitions.

Results: The search term 'MOAHLFA' was used in 35 publications from a broad geographical origin. More than 80% of the 24 participants of the survey (65% response) agreed on maintaining to use (i) sex for the 'M' criterion, (ii) occupation-related dermatitis irrespective of medicolegal definitions for the 'O', (iii) atopic dermatitis (but not rhinitis or asthma) for the 'A'. The possibility to use more than one site among 'H', 'L' and 'F' and a more detailed description of age distribution were favoured, and the difficult interpretability of the 'P' measure was highlighted.

Conclusions: The 'classical' MOAHLFA(P) index may be extended. Some aspects, notably atopic dermatitis, need further standardisation.

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“MOAHLFA(P)指数”：尝试标准化广泛使用的贴片检测患者描述符阵列。

背景：自 1980 年推出以来，MOHL 指数（男性、职业性皮炎、手部皮炎或腿部皮炎患者的百分比）及其后来的演变，直至目前使用的 MOAHLFA(P) 指数（添加特应性皮炎、面部皮炎、年龄在 40 岁以上且对≥ 1 种基线系列过敏原呈阳性反应的患者的百分比）都旨在传达在特定地区和时间进行贴片测试的患者的重要人口统计学和临床信息，从而帮助解释观察到的致敏谱系：研究 MOAHLFA(P)指数的当前使用情况，并对其单项的综合定义提出建议：方法：在 Medline 中进行标题/摘要检索，找出提及不断演变的缩写的出版物。在接触性皮炎专家中进行德尔菲式调查，收集对建议定义的一致意见：结果：搜索词 "MOAHLFA "出现在 35 篇来自不同地区的出版物中。在 24 位参与调查的人员中，超过 80% 的人员（65% 的回复率）同意坚持使用以下标准：(i) 性别作为 "M "标准；(ii) 职业相关皮炎（无论医学法律定义如何）作为 "O "标准；(iii) 特应性皮炎（但不包括鼻炎或哮喘）作为 "A "标准。在 "H"、"L "和 "F "中使用一个以上部位的可能性以及对年龄分布的更详细描述受到青睐，"P "指标难以解释的问题也得到了强调：结论："经典 "的 MOAHLFA（P）指数可以扩展。结论："经典 "MOAHLFA（P）指数可以扩展，但某些方面（尤其是特应性皮炎）需要进一步标准化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Contact Dermatitis 医学-过敏

CiteScore

4.60

自引率

30.90%

发文量

227

审稿时长

4-8 weeks

期刊介绍： Contact Dermatitis is designed primarily as a journal for clinicians who are interested in various aspects of environmental dermatitis. This includes both allergic and irritant (toxic) types of contact dermatitis, occupational (industrial) dermatitis and consumers" dermatitis from such products as cosmetics and toiletries. The journal aims at promoting and maintaining communication among dermatologists, industrial physicians, allergists and clinical immunologists, as well as chemists and research workers involved in industry and the production of consumer goods. Papers are invited on clinical observations, diagnosis and methods of investigation of patients, therapeutic measures, organisation and legislation relating to the control of occupational and consumers".