Imaging appearances of perinephric myxoid pseudotumor of fat (PMPF)

IF 2.1 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical radiology Pub Date : 2025-02-01 DOI:10.1016/j.crad.2024.106775

M. Sugi, A. Lombardi, I. Krishnan, K. Sandrasegaran

{"title":"Imaging appearances of perinephric myxoid pseudotumor of fat (PMPF)","authors":"M. Sugi, A. Lombardi, I. Krishnan, K. Sandrasegaran","doi":"10.1016/j.crad.2024.106775","DOIUrl":null,"url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to identify the imaging feature of perinephric myxoid pseudotumor of fat (PMPF) in a large cohort.</div></div><div><h3>Materials and Methods</h3><div>Institutional radiology and pathology databases were queried for PMPF for the period from January 2010 to December 2023. Of the 22 identified individuals, two were excluded due to nonavailability of computed tomography (CT) or magnetic resonance (MR) images and five due to lack of pathological confirmation. The study cohort comprised of 15 individuals (males = 10), with median age of 59 years (range: 26–87 years). Three abdominal radiologists in consensus reviewed all relevant CT, magnetic resonance imaging (MRI) and positron emission tomography (PET) images.</div></div><div><h3>Results</h3><div>Seventeen tumuors were analysed since two individuals had bilateral tumuors. The tumuors were at the renal hilum (n=7) or perinephric space (n=10). Two imaging patterns were seen: hazy ill-defined predominantly fatty mass (n=9) or a soft tissue mass (n=8) with variable fat content (0–90%). At presentation, the tumuors ranged in size from 1.5 to 16.5 cm (median: 6.2 cm). The perihilar tumuors encased central renal vessels without occlusion or thrombus. Ureteric encasement and mild hydronephrosis were seen in 11 and 4 tumuors, respectively. Most (9 of 13) of the affected native kidneys and all transplant kidneys (n=5) showed parenchymal poor contrast enhancement. Tumuors with greater than 12-month follow-up (n=11) showed a median growth of 15%.</div></div><div><h3>Conclusion</h3><div>PMPF may be considered in the diagnosis of tumuors with soft tissue and fat components situated at the renal hilum or perinephric space. The delayed contrast enhancement, relative lack of mass effect for size, and poor function of affected kidney are diagnostic features.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"Article 106775"},"PeriodicalIF":2.1000,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical radiology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0009926024006627","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}

引用次数: 0

Abstract

Aim

This study aimed to identify the imaging feature of perinephric myxoid pseudotumor of fat (PMPF) in a large cohort.

Materials and Methods

Institutional radiology and pathology databases were queried for PMPF for the period from January 2010 to December 2023. Of the 22 identified individuals, two were excluded due to nonavailability of computed tomography (CT) or magnetic resonance (MR) images and five due to lack of pathological confirmation. The study cohort comprised of 15 individuals (males = 10), with median age of 59 years (range: 26–87 years). Three abdominal radiologists in consensus reviewed all relevant CT, magnetic resonance imaging (MRI) and positron emission tomography (PET) images.

Results

Seventeen tumuors were analysed since two individuals had bilateral tumuors. The tumuors were at the renal hilum (n=7) or perinephric space (n=10). Two imaging patterns were seen: hazy ill-defined predominantly fatty mass (n=9) or a soft tissue mass (n=8) with variable fat content (0–90%). At presentation, the tumuors ranged in size from 1.5 to 16.5 cm (median: 6.2 cm). The perihilar tumuors encased central renal vessels without occlusion or thrombus. Ureteric encasement and mild hydronephrosis were seen in 11 and 4 tumuors, respectively. Most (9 of 13) of the affected native kidneys and all transplant kidneys (n=5) showed parenchymal poor contrast enhancement. Tumuors with greater than 12-month follow-up (n=11) showed a median growth of 15%.

Conclusion

PMPF may be considered in the diagnosis of tumuors with soft tissue and fat components situated at the renal hilum or perinephric space. The delayed contrast enhancement, relative lack of mass effect for size, and poor function of affected kidney are diagnostic features.

查看原文本刊更多论文

肾周黏液性脂肪假瘤（PMPF）的影像学表现。

目的：本研究旨在确定大队列肾盂周围黏液样假性脂肪瘤（PMPF）的影像学特征。材料和方法：查询2010年1月至2023年12月期间各机构放射学和病理学数据库的PMPF。在22名确诊患者中，2名因无法获得计算机断层扫描（CT）或磁共振（MR）图像而被排除，5名因缺乏病理证实而被排除。研究队列包括15人（男性= 10人），年龄中位数为59岁（范围：26-87岁）。三位腹部放射科医生一致审查了所有相关的CT，磁共振成像（MRI）和正电子发射断层扫描（PET）图像。结果：两例双侧肿瘤共17例。肿瘤位于肾门（n=7）或肾周间隙（n=10）。可见两种成像模式：模糊不清的主要脂肪块（n=9）或软组织块（n=8），脂肪含量变化（0-90%）。出现时，肿瘤大小为1.5 ~ 16.5 cm（中位：6.2 cm）。门静脉周围肿瘤包裹肾中央血管，无阻塞或血栓。输尿管梗阻11例，轻度肾积水4例。大多数（9 / 13）受影响的原生肾脏和所有移植肾脏（n=5）显示实质增强较差。随访超过12个月的肿瘤（n=11）中位生长为15%。结论：PMPF在肾门或肾周间隙有软组织和脂肪成分的肿瘤的诊断中有一定的价值。延迟增强、相对缺乏体积效应、受累肾脏功能差是诊断特征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical radiology 医学-核医学

CiteScore

4.70

自引率

3.80%

发文量

528

审稿时长

76 days

期刊介绍： Clinical Radiology is published by Elsevier on behalf of The Royal College of Radiologists. Clinical Radiology is an International Journal bringing you original research, editorials and review articles on all aspects of diagnostic imaging, including: • Computed tomography • Magnetic resonance imaging • Ultrasonography • Digital radiology • Interventional radiology • Radiography • Nuclear medicine Papers on radiological protection, quality assurance, audit in radiology and matters relating to radiological training and education are also included. In addition, each issue contains correspondence, book reviews and notices of forthcoming events.