Anthony D LaMontagne, Christopher Lockwood, Andrew Mackinnon, David Henry, Laura Cox, Neil R Hall, Tania L King
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引用次数: 0
Abstract
Background: The MATES in Construction suicide prevention program was adapted to the manufacturing sector and evaluated in a pilot of the program.
Methods: Ten manufacturing worksites were randomly assigned to intervention (5 sites) and wait-list control (5 sites) conditions in a two-arm cluster randomized design. 1245 workers responded at baseline (87% response rate) and 648 at final (35% response rate). Literacy of Suicide Scale (LOSS) was assessed as a process outcome, and help-seeking intentions as the primary outcome (General Help-Seeking Questionnaire [GHSQ] score). Secondary outcomes included help sought, suicidal thoughts and likelihood of suicide attempt scores, and Kessler-6 scores. Linear mixed models for repeated measures were used in intention-to-treat (ITT) and completer analyses.
Results: All sites finished the trial, with intervention periods ranging from 8 to 11 months; however, none of the five intervention sites fully implemented the intervention as planned. ITT analyses showed an improvement in LOSS scores within the intervention group (0.49, 95% CI 0.13-0.49), but the mean difference in change between intervention and control included the null (0.34, 95% CI -0.10 to 0.80). The primary outcome of GHSQ scores also improved within the intervention group, but the difference in change included the null (mean difference 1.52, 95% CI -0.69 to 3.74). No secondary outcomes improved relative to control in ITT or completers analyses. Exploratory analysis of disaggregated GHSQ help sources showed greater improvement in mean difference in change for the main MATES message of seeking help from MATES Connectors.
Conclusion: The intervention, as implemented, was not effective at achieving the primary or secondary outcomes.
Trial registration: Australian and New Zealand Clinical Trial Registry: ACTRN 12622000122752.
背景:建筑自杀预防计划的MATES适用于制造业,并在该计划的试点中进行评估。方法:采用双组随机设计,将10个生产车间随机分为干预组(5个)和等候组(5个)。1245名工人在基线(87%的回复率),648名工人在最终(35%的回复率)。自杀量表读写能力(LOSS)作为过程结果进行评估,寻求帮助意愿作为主要结果(一般寻求帮助问卷[GHSQ]评分)。次要结果包括寻求帮助,自杀想法和自杀企图的可能性得分,以及Kessler-6得分。在意向治疗(ITT)和完整分析中使用了重复测量的线性混合模型。结果:所有试验点均完成试验,干预期8 ~ 11个月;然而,五个干预点中没有一个完全按照计划实施干预。ITT分析显示干预组的LOSS评分有所改善(0.49,95% CI 0.13-0.49),但干预组和对照组之间的平均变化差异包括null (0.34, 95% CI -0.10至0.80)。干预组中GHSQ评分的主要结局也有所改善,但变化的差异包括零值(平均差异1.52,95% CI -0.69至3.74)。在ITT或完成者分析中,相对于对照组,次要结局没有改善。对分解的GHSQ帮助来源的探索性分析显示,从MATES连接器寻求帮助的主要MATES信息的平均变化差异有更大的改善。结论:该干预措施在实现主要或次要结局方面并不有效。试验注册:澳大利亚和新西兰临床试验注册:ACTRN 12622000122752。
期刊介绍:
American Journal of Industrial Medicine considers for publication reports of original research, review articles, instructive case reports, and analyses of policy in the fields of occupational and environmental health and safety. The Journal also accepts commentaries, book reviews and letters of comment and criticism. The goals of the journal are to advance and disseminate knowledge, promote research and foster the prevention of disease and injury. Specific topics of interest include: occupational disease; environmental disease; pesticides; cancer; occupational epidemiology; environmental epidemiology; disease surveillance systems; ergonomics; dust diseases; lead poisoning; neurotoxicology; endocrine disruptors.