Outcomes of fetuses with severe diaphragmatic hernia after fetal endoluminal tracheal occlusion treatment: A series of case reports

IF 2 4区医学 Q2 OBSTETRICS & GYNECOLOGY

Taiwanese Journal of Obstetrics & Gynecology Pub Date : 2025-01-01 DOI:10.1016/j.tjog.2024.09.024

ChunYan Zhong , XiaoHang Zhang , SuZhen Ran

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引用次数: 0

Abstract

Objective

To explore outcomes of fetuses with severe congenital diaphragmatic hernia (CDH) after fetal endoluminal tracheal occlusion (FETO) treatment.

Case report

Fetuses diagnosed with severe CDH and taken FETO for intrauterine treatment from January 2020 to December 2023 were recruited. There was no significant difference in general conditions, as well as O/E LHR and measurements related to CDH (p > 0.05). All babies were born prematurely. One got poor Apgar score and died soon after birth and 3 died after treatment in NICU for some time. Only one associated with congenital cystic adenomatoid malformation (CCAM) was survived and got good outcome after long time follow-up. It seemed CCAM associated occupying a part volume of left thorax which may help to protect abdominal organs from herniating.

Conclusion

FETO treatment may not improve the survival rate of severe CDH significantly, but associated with CCAM may helpful to protect abdominal organs from herniating.

查看原文本刊更多论文

胎儿腔内气管闭塞治疗后严重膈疝胎儿的预后：一系列病例报告。

目的：探讨重度先天性膈疝（CDH）胎儿气管内闭塞（FETO）治疗后的预后。病例报告：招募2020年1月至2023年12月诊断为重度CDH并接受FETO宫内治疗的胎儿。一般情况下，O/E LHR和CDH相关测量无显著差异（p < 0.05）。所有的婴儿都是早产儿。1例Apgar评分较差，出生后不久死亡，3例在新生儿重症监护病房治疗一段时间后死亡。仅有1例合并先天性囊性腺瘤样畸形（CCAM）存活，经长时间随访，预后良好。CCAM相关占据左胸部分体积，可能有助于保护腹部器官免于疝出。结论：FETO治疗不能显著提高重症CDH的生存率，但联合CCAM可能有助于保护腹部脏器不发生疝出。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Taiwanese Journal of Obstetrics & Gynecology OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

23.80%

发文量

207

审稿时长

4-8 weeks

期刊介绍： Taiwanese Journal of Obstetrics and Gynecology is a peer-reviewed journal and open access publishing editorials, reviews, original articles, short communications, case reports, research letters, correspondence and letters to the editor in the field of obstetrics and gynecology. The aims of the journal are to: 1.Publish cutting-edge, innovative and topical research that addresses screening, diagnosis, management and care in women''s health 2.Deliver evidence-based information 3.Promote the sharing of clinical experience 4.Address women-related health promotion The journal provides comprehensive coverage of topics in obstetrics & gynecology and women''s health including maternal-fetal medicine, reproductive endocrinology/infertility, and gynecologic oncology. Taiwan Association of Obstetrics and Gynecology.