Sex differences in resting-state fMRI functional connectivity related to humor styles.

IF 2.7 3区医学 Q1 BEHAVIORAL SCIENCES

Biological Psychology Pub Date : 2025-01-01 Epub Date: 2025-01-08 DOI:10.1016/j.biopsycho.2025.108983

Chia-Yueh Chang, Yu-Chen Chan, I-Fei Chen, Hsueh-Chih Chen

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引用次数: 0

Abstract

Research on how functional connectivity (FC) during resting-state relates to humor styles and sex is limited. This study aimed to address this knowledge gap by analyzing resting-state fMRI data from 56 healthy participants and measuring FC. In addition, participants completed the Humor Styles Questionnaire. We found distinct FC patterns linked to humor styles that differed by sex. Men demonstrated stronger FC between the anterior cingulate cortex (ACC) and the right anterior insula (rAI), right inferior frontal gyrus (rIFG) and right frontal pole (rFP), and between the right rostral prefrontal cortex (rRPFC) and rIFG. These patterns were associated with aggressive and self-enhancing humor. Conversely, women exhibited stronger FC between rRPFC and the posterior cingulate gyrus (PCC), left rostral prefrontal cortex (lRPFC) and right thalamus, correlating with self-defeating and less aggressive humor. These findings suggest a neurobiological basis for sex differences in humor, indicating that men's FC between the salience network (SN), particularly in cognitive monitoring regions, may be linked to aggressive humor. Their FC between the executive control network (ECN) and between the SN and ECN are related to self-enhancing humor and reflect an emphasis on executive function. Conversely, women's FC between the SN and default mode network is correlated with self-defeating humor, suggesting a stronger focus on self-reflection and social relationships.

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幽默风格相关静息状态fMRI功能连通性的性别差异。

关于静息状态下功能连接（FC）与幽默风格和性别之间关系的研究有限。本研究旨在通过分析来自56名健康参与者的静息状态fMRI数据并测量FC来解决这一知识差距。此外，参与者还完成了幽默风格问卷。我们发现不同性别的FC模式与幽默风格有关。男性在前扣带皮层（ACC）与右前叶岛（rAI）、右额下回（rIFG）与右额极（rFP）、右吻侧前额叶皮层（rRPFC）与rIFG之间表现出更强的FC。这些模式与侵略性和自我提升的幽默有关。相反，女性在rRPFC与后扣带回（PCC）、左吻侧前额叶皮层（lRPFC）和右丘脑之间表现出更强的FC，与自我挫败和较少的攻击性幽默相关。这些发现提示了幽默的性别差异的神经生物学基础，表明男性的突出网络（SN）之间的FC，特别是在认知监测区域，可能与攻击性幽默有关。他们的执行控制网络（ECN）之间以及SN和ECN之间的FC与自我增强幽默有关，反映了对执行功能的重视。相反，女性在SN和默认模式网络之间的FC与自我挫败的幽默相关，这表明女性更注重自我反思和社会关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biological Psychology 医学-行为科学

CiteScore

4.20

自引率

11.50%

发文量

146

审稿时长

3 months

期刊介绍： Biological Psychology publishes original scientific papers on the biological aspects of psychological states and processes. Biological aspects include electrophysiology and biochemical assessments during psychological experiments as well as biologically induced changes in psychological function. Psychological investigations based on biological theories are also of interest. All aspects of psychological functioning, including psychopathology, are germane. The Journal concentrates on work with human subjects, but may consider work with animal subjects if conceptually related to issues in human biological psychology.