State of the Art in Left Atrial Appendage Occlusion

IF 8 1区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

JACC. Clinical electrophysiology Pub Date : 2025-03-01 DOI:10.1016/j.jacep.2024.10.024

Jalaj Garg MD , Rajesh Kabra MD , Rakesh Gopinathannair MD , Luigi Di Biase MD, PhD , Dee Dee Wang MD , Jacqueline Saw MD , Rebecca Hahn MD , James V. Freeman MD , Christopher R. Ellis MD , Dhanunjaya Lakkireddy MD

引用次数: 0

Abstract

Left atrial appendage occlusion (LAAO) has become an important therapeutic target for stroke prevention in patients with nonvalvular atrial fibrillation. Over the past 2 decades, several advancements in LAAO devices (percutaneous and surgical) have been made for stroke prevention and arrhythmia therapy. However, there are several unanswered questions regarding optimal patient selection, the preferred LAAO approach and device, the management of periprocedural and postprocedural complications, including pericardial effusion, device-related thrombus, and device leaks. This review focuses on fundamental foundational concepts in various aspects of the left atrial appendage and management strategies as they relate to current clinical needs.

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左心耳闭塞术的研究现状。

左心耳闭塞术已成为预防非瓣膜性心房颤动患者脑卒中的重要治疗靶点。在过去的20年里，LAAO装置（经皮和手术）在预防中风和治疗心律失常方面取得了一些进展。然而，关于最佳患者选择、首选LAAO入路和装置、术中和术后并发症（包括心包积液、装置相关血栓和装置泄漏）的处理，仍有几个悬而未决的问题。这篇综述的重点是基本的基本概念在各个方面的左心耳和管理策略，因为他们涉及到当前的临床需要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

JACC. Clinical electrophysiology CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

10.30

自引率

5.70%

发文量

250

期刊介绍： JACC: Clinical Electrophysiology is one of a family of specialist journals launched by the renowned Journal of the American College of Cardiology (JACC). It encompasses all aspects of the epidemiology, pathogenesis, diagnosis and treatment of cardiac arrhythmias. Submissions of original research and state-of-the-art reviews from cardiology, cardiovascular surgery, neurology, outcomes research, and related fields are encouraged. Experimental and preclinical work that directly relates to diagnostic or therapeutic interventions are also encouraged. In general, case reports will not be considered for publication.