Prevalence of chronic hand eczema in adults: a cross-sectional survey of over 60 000 respondents from the general population of Canada, France, Germany, Italy, Spain and the UK.

IF 11 1区 医学 Q1 DERMATOLOGY
Christian Apfelbacher, Anthony Bewley, Sonja Molin, Maria Concetta Fargnoli, Ana Maria Giménez-Arnau, Lysel Brignoli, Bleuenn Rault, Jenny M Norlin, Tea Skaaby, Marie-Noëlle Crépy
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引用次数: 0

Abstract

Background: The lack of attention paid to chronic hand eczema (CHE) and the lack of a specific International Classification of Diseases code for it may have limited assessment of its prevalence. To date, prevalence estimates have primarily been derived from (partly small) single-country studies.

Objectives: To estimate the annual prevalence of self-reported physician-diagnosed CHE across sociodemographic characteristics in adults living in Canada, France, Germany, Italy, Spain and the UK.

Methods: In the observational Chronic Hand Eczema epidemiology, Care, and Knowledge of real-life burden (CHECK) study, a questionnaire was administered to adults aged 18-69 years in the general population, recruited through online panels. Quotas and minor weighting adjustments were performed to ensure that the participants were representative of the general population with regard to sex, age, region, employment status, urban/rural setting and - in the UK only - ethnicity. Additional weights were applied to account for population size differences when aggregating country results. Information on self-reported physician-diagnosed CHE was collected. CHE was defined, in accordance with the European Society of Contact Dermatitis, as having had hand eczema continuously for ≥ 3 months or at least two flares in the past 12 months. The annual prevalence of CHE was determined for each country, and by subgroups of sex, age, employment and urban/rural setting.

Results: Of 60 131 participants, 2847 self-reported physician-diagnosed CHE, yielding an annual prevalence of 4.7% [95% confidence interval (CI) 4.6-4.9]. Subgroup analyses revealed that the prevalence of CHE was significantly higher in women than in men [5.6% (95% CI 5.4-5.9) vs. 3.8% (95% CI 3.6-4.1); P < 0.001], in employed vs. unemployed people [5.3% (95% CI 5.1-5.6) vs. 3.3% (95% CI 3.1-3.6); P < 0.001] and in urban vs. rural residents [5.0% (95% CI 4.8-5.2) vs. 3.7% (95% CI 3.4-4.1); P < 0.001). Prevalence was highest in those aged 30-39 years (6.5%, 95% CI 6.0-7.0) and lowest in those aged 60-69 years (2.6%, 95% CI 2.3-3.0).

Conclusions: This large multinational study is the first to assess the prevalence of CHE in Europe and Canada using a consistent definition across a broad geographical population. This study reveals that CHE is a common skin disease with annual prevalence of 4.7%, with a higher prevalence in women, people aged 30-39, employed people and those living in urban areas.

成人慢性手部湿疹的患病率:对加拿大、法国、德国、意大利、西班牙和英国6万多名普通人群的横断面调查。
背景:缺乏对慢性手湿疹(CHE)的关注和缺乏针对CHE的特定国际疾病分类代码可能限制了对CHE患病率的评估。迄今为止,患病率估计主要来自(部分规模较小的)单一国家研究。目的:估计加拿大、法国、德国、意大利、西班牙和英国成年人中自我报告的医生诊断的CHE的年患病率。方法:在这项观察性慢性手部湿疹流行病学、护理和现实生活负担知识(CHECK)研究中,通过在线小组对18至69岁的普通人群进行问卷调查。进行了配额和轻微的权重调整,以确保参与者在性别、年龄、地区、就业状况、城市/农村环境以及(仅在英国)种族方面代表一般人口。在汇总国家结果时,采用了额外的权重来解释人口规模的差异。收集了自我报告的医生诊断的CHE信息。根据欧洲接触性皮炎协会的定义,CHE是指手部湿疹持续三个月或以上,或在过去12个月内至少有两次发作。每个国家按性别、年龄、就业和城市/农村亚组确定了CHE的年患病率,95%置信区间(ci)。结果:在60131名参与者中,2847名自我报告为医生诊断的CHE,年患病率为4.7% (CI: 4.6-4.9)。亚组分析显示,女性的CHE患病率明显高于男性(5.6% [5.4-5.9]vs. 3.8% [3.6-4.1]);结论:这项大型跨国研究首次在欧洲和加拿大广泛的地理人群中使用一致的定义来评估CHE患病率。本研究表明,CHE是一种常见的皮肤病,年患病率为4.7%,在女性、30-39岁人群、就业人群和城市居民中患病率较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
British Journal of Dermatology
British Journal of Dermatology 医学-皮肤病学
CiteScore
16.30
自引率
3.90%
发文量
1062
审稿时长
2-4 weeks
期刊介绍: The British Journal of Dermatology (BJD) is committed to publishing the highest quality dermatological research. Through its publications, the journal seeks to advance the understanding, management, and treatment of skin diseases, ultimately aiming to improve patient outcomes.
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