{"title":"Tomato fruit ripening is modulated by redox modification of RNA demethylase","authors":"","doi":"10.1038/s41477-024-01900-y","DOIUrl":null,"url":null,"abstract":"This study reveals that the RNA N6-methyladenosine (m6A) demethylase SlALKBH2 undergoes a reduction–oxidation (redox) modification in which hydrogen peroxide mediates the oxidation and the reductase SlNTRC catalyses the reduction. This redox modification affects SlALKBH2 protein stability, thereby modulating its physiological function in the regulation of normal ripening of tomato fruits.","PeriodicalId":18904,"journal":{"name":"Nature Plants","volume":"36 1","pages":""},"PeriodicalIF":15.8000,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Plants","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1038/s41477-024-01900-y","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PLANT SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
This study reveals that the RNA N6-methyladenosine (m6A) demethylase SlALKBH2 undergoes a reduction–oxidation (redox) modification in which hydrogen peroxide mediates the oxidation and the reductase SlNTRC catalyses the reduction. This redox modification affects SlALKBH2 protein stability, thereby modulating its physiological function in the regulation of normal ripening of tomato fruits.
期刊介绍:
Nature Plants is an online-only, monthly journal publishing the best research on plants — from their evolution, development, metabolism and environmental interactions to their societal significance.