Heating up three cold cases in Norway using investigative genetic genealogy.

Håvard Aanes, Magnus D Vigeland, Bastiaan Star, Gregor D Gilfillan, Morten Mattingsdal, Simon Trøan, Monica Strand, Leif Morten Eide, Eirik Natås Hanssen
{"title":"Heating up three cold cases in Norway using investigative genetic genealogy.","authors":"Håvard Aanes, Magnus D Vigeland, Bastiaan Star, Gregor D Gilfillan, Morten Mattingsdal, Simon Trøan, Monica Strand, Leif Morten Eide, Eirik Natås Hanssen","doi":"10.1016/j.fsigen.2024.103217","DOIUrl":null,"url":null,"abstract":"<p><p>With the advent of commercial DNA databases, investigative genetic genealogy (IGG) has emerged as a powerful forensic tool, rivalling the impact of STR analyses, introduced four decades ago. IGG has been frequently applied in the US and tested in other countries, but never in Norway. Here, we apply IGG to three cold criminal cases and successfully identify the donor of the DNA in two of these cases. Our findings suggest that when combined with phenotypic prediction and case information, IGG holds substantial potential for resolving both active and cold cases in Norway. This potential is amplified by the digitalization of archives and the transparent and structured nature of society in Norway. Additionally, the databases exhibit sufficient representation to yield matches with distant relatives. Moreover, this work has uncovered a series of lingering research questions spanning the entire workflow from DNA extraction to genealogy research. Finally, we highlight the possibility that more insights can be gleaned from genetic profiles, for instance using an accurate age prediction method. The results show that IGG can be successfully applied in Norway, having reached a level of maturity that enables identification of unknown individuals in cases where DNA is accessible.</p>","PeriodicalId":94012,"journal":{"name":"Forensic science international. Genetics","volume":"76 ","pages":"103217"},"PeriodicalIF":0.0000,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forensic science international. Genetics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.fsigen.2024.103217","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

With the advent of commercial DNA databases, investigative genetic genealogy (IGG) has emerged as a powerful forensic tool, rivalling the impact of STR analyses, introduced four decades ago. IGG has been frequently applied in the US and tested in other countries, but never in Norway. Here, we apply IGG to three cold criminal cases and successfully identify the donor of the DNA in two of these cases. Our findings suggest that when combined with phenotypic prediction and case information, IGG holds substantial potential for resolving both active and cold cases in Norway. This potential is amplified by the digitalization of archives and the transparent and structured nature of society in Norway. Additionally, the databases exhibit sufficient representation to yield matches with distant relatives. Moreover, this work has uncovered a series of lingering research questions spanning the entire workflow from DNA extraction to genealogy research. Finally, we highlight the possibility that more insights can be gleaned from genetic profiles, for instance using an accurate age prediction method. The results show that IGG can be successfully applied in Norway, having reached a level of maturity that enables identification of unknown individuals in cases where DNA is accessible.

利用基因系谱研究挪威的三起悬案。
随着商业DNA数据库的出现,调查基因谱系(IGG)已经成为一种强大的法医工具,与40年前引入的STR分析的影响相媲美。IGG经常在美国应用,在其他国家进行检测,但从未在挪威进行过。在这里,我们将IGG应用于三个悬案,并成功地确定了其中两个案件的DNA供体。我们的研究结果表明,当与表型预测和病例信息相结合时,IGG在解决挪威的活跃病例和感冒病例方面具有巨大的潜力。档案的数字化以及挪威社会的透明和结构化,放大了这一潜力。此外,数据库表现出足够的代表性,以产生与远亲的匹配。此外,这项工作还揭示了一系列挥之不去的研究问题,涵盖了从DNA提取到家谱研究的整个工作流程。最后,我们强调了从基因图谱中收集更多信息的可能性,例如使用准确的年龄预测方法。结果表明,IGG可以在挪威成功应用,已经达到成熟的水平,可以在DNA可获得的情况下识别未知个体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信