Volumetric measurement of manually drawn segmentations in cone beam computed tomography images of newly formed bone after sinus floor augmentation with bovine-derived bone substitutes.

IF 2.2 3区医学 Q2 Dentistry

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-01-04 DOI:10.1016/j.jormas.2025.102221

Pascal Grün, Sepideh Hatamikia, Tim Lakes, Benedikt Schneider, Florian Pfaffeneder-Mantai, Sebastian Fitzek, Constantin von See, Dritan Turhani

{"title":"Volumetric measurement of manually drawn segmentations in cone beam computed tomography images of newly formed bone after sinus floor augmentation with bovine-derived bone substitutes.","authors":"Pascal Grün, Sepideh Hatamikia, Tim Lakes, Benedikt Schneider, Florian Pfaffeneder-Mantai, Sebastian Fitzek, Constantin von See, Dritan Turhani","doi":"10.1016/j.jormas.2025.102221","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Precise volumetric measurement of newly formed bone after maxillary sinus floor augmentation (MSFA) can help clinicians in planning for dental implants. This study aimed to introduce a novel modular framework to facilitate volumetric calculations based on manually drawn segmentations of user-defined areas of interest on cone-beam computed tomography (CBCT) images MATERIAL & METHODS: Two interconnected networks for manual segmentation of a defined volume of interest and dental implant volume calculation, respectively, were used in parallel. The volume data of dental implant manufacturers were used for reference. The efficacy of this framework was demonstrated through practical applications for collecting CBCT data from patients after MSFA with the same quantity of two different bovine-derived bone substitutes: xenohybrid composite bone (Group I, n = 10) and hydroxyapatite (Group II, n = 10). The study was approved by the central Ethical Review Board of the federal state of Lower Austria (approval number: GS4-EK-4/451-2021). The volumes were measured immediately (T1) and 6 months (T2) after MSFA and before insertion of the dental implant. All measurements were analyzed for inter- and intravariability. P-values of >0.05 were obtained from the t-test analysis RESULTS: The manual delineation of Group II (n = 10) was easier than that of Group I (n = 10) due to the visual contrast of the CBCT scan. The mean volume was 861.65 ± 290.02 mm³ at T1 and 875.9 ± 288.96 mm³ at T2. This shows a moderate dispersion around the mean value, which indicates variability of the analyzed data DISCUSSION: The proposed network may be useful for the development of computer-based diagnostic systems for assessing the success of MSFA with bone replacement materials. The volumetric stability achieved with the two bone replacement materials were comparable.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102221"},"PeriodicalIF":2.2000,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Stomatology Oral and Maxillofacial Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jormas.2025.102221","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Dentistry","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction: Precise volumetric measurement of newly formed bone after maxillary sinus floor augmentation (MSFA) can help clinicians in planning for dental implants. This study aimed to introduce a novel modular framework to facilitate volumetric calculations based on manually drawn segmentations of user-defined areas of interest on cone-beam computed tomography (CBCT) images MATERIAL & METHODS: Two interconnected networks for manual segmentation of a defined volume of interest and dental implant volume calculation, respectively, were used in parallel. The volume data of dental implant manufacturers were used for reference. The efficacy of this framework was demonstrated through practical applications for collecting CBCT data from patients after MSFA with the same quantity of two different bovine-derived bone substitutes: xenohybrid composite bone (Group I, n = 10) and hydroxyapatite (Group II, n = 10). The study was approved by the central Ethical Review Board of the federal state of Lower Austria (approval number: GS4-EK-4/451-2021). The volumes were measured immediately (T1) and 6 months (T2) after MSFA and before insertion of the dental implant. All measurements were analyzed for inter- and intravariability. P-values of >0.05 were obtained from the t-test analysis RESULTS: The manual delineation of Group II (n = 10) was easier than that of Group I (n = 10) due to the visual contrast of the CBCT scan. The mean volume was 861.65 ± 290.02 mm³ at T1 and 875.9 ± 288.96 mm³ at T2. This shows a moderate dispersion around the mean value, which indicates variability of the analyzed data DISCUSSION: The proposed network may be useful for the development of computer-based diagnostic systems for assessing the success of MSFA with bone replacement materials. The volumetric stability achieved with the two bone replacement materials were comparable.

查看原文本刊更多论文

牛源性骨替代物窦底增强后新形成骨的锥形束计算机断层图像中人工绘制分割的体积测量。

上颌窦底增强术（MSFA）后新生骨的精确体积测量可以帮助临床医生计划种植牙。本研究旨在引入一种新的模块化框架，以促进基于锥形束计算机断层扫描（CBCT）图像上用户自定义感兴趣区域的手动分割的体积计算。材料与方法：两个相互连接的网络分别用于手动分割定义的感兴趣体积和牙科种植体体积计算。参考种植体生产厂家的体积数据。该框架的有效性通过使用相同数量的两种不同的牛源性骨替代物：异种复合骨（组I， n = 10）和羟基磷灰石（组II， n = 10）收集MSFA后患者的CBCT数据的实际应用得到了证明。该研究已获得下奥地利联邦州中央伦理审查委员会的批准（批准号：GS4-EK-4/451-2021）。在MSFA后即刻（T1）和植入种植体前6个月（T2）测量体积。对所有测量结果进行内部变异性和体内变异性分析。结果：由于CBCT扫描的视觉对比，II组（n = 10）比I组（n = 10）更容易人工圈定。T1时平均体积为861.65±290.02 mm³，T2时平均体积为875.9±288.96 mm³。这表明在平均值周围有适度的分散，这表明分析数据的可变性。讨论：所提出的网络可能有助于开发基于计算机的诊断系统，以评估骨替代材料MSFA的成功。两种骨替代材料的体积稳定性相当。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Stomatology Oral and Maxillofacial Surgery Dentistry-Oral Surgery

CiteScore

2.20

自引率

9.10%

发文量

305

期刊介绍： J Stomatol Oral Maxillofac Surg publishes research papers and techniques - (guest) editorials, original articles, reviews, technical notes, case reports, images, letters to the editor, guidelines - dedicated to enhancing surgical expertise in all fields relevant to oral and maxillofacial surgery: from plastic and reconstructive surgery of the face, oral surgery and medicine, … to dentofacial and maxillofacial orthopedics. Original articles include clinical or laboratory investigations and clinical or equipment reports. Reviews include narrative reviews, systematic reviews and meta-analyses. All manuscripts submitted to the journal are subjected to peer review by international experts, and must: Be written in excellent English, clear and easy to understand, precise and concise; Bring new, interesting, valid information - and improve clinical care or guide future research; Be solely the work of the author(s) stated; Not have been previously published elsewhere and not be under consideration by another journal; Be in accordance with the journal''s Guide for Authors'' instructions: manuscripts that fail to comply with these rules may be returned to the authors without being reviewed. Under no circumstances does the journal guarantee publication before the editorial board makes its final decision. The journal is indexed in the main international databases and is accessible worldwide through the ScienceDirect and ClinicalKey Platforms.