Effect of low birth weight and preterm delivery on the development of childhood celiac disease: a systematic review and meta-analysis on observational studies.

IF 2.6 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Current Opinion in Gastroenterology Pub Date : 2025-01-03 DOI:10.1097/MOG.0000000000001074

Mansour Bahardoust, Ali Delpisheh, Shabnam Rashidi, Meisam Haghmoradi, Babak Goodarzy, Reza Mahdian Jouybari

{"title":"Effect of low birth weight and preterm delivery on the development of childhood celiac disease: a systematic review and meta-analysis on observational studies.","authors":"Mansour Bahardoust, Ali Delpisheh, Shabnam Rashidi, Meisam Haghmoradi, Babak Goodarzy, Reza Mahdian Jouybari","doi":"10.1097/MOG.0000000000001074","DOIUrl":null,"url":null,"abstract":"Purpose of review: Whether low birth weight (LBW) and preterm delivery (PD) are associated with the risk of developing celiac disease (CD) in children remains unclear. This systematic review and meta-analysis aimed to evaluate the association between LBW and PD with CD development in children.Recent findings: We searched PubMed, Embase, Scopus, Web of Science, and Google Scholar databases based on the Mesh terms to find observational studies that investigated the association of LBW and PD with CD development in children up to July 18, 2024. This systematic review was based on the PRISMA 2020 checklist. Heterogeneity between studies was assessed with Cochran's Q and I2 tests. Meta-regression was used to control heterogeneity. Publication bias was evaluated using Egger's test. Finally, ten studies involving 3 434 290 participants were included. Based on 10 studies, the pooled prevalence of LBW was 6.4 per 1000 children with CD. A pooled estimate of ten studies did not show a significant relationship between LBW and the risk of developing CD in children [odds ratio (OR): 0.96, 95% confidence interval (CI): 0.76, 1.16, I2: 67.9%, P: 0.001). Also, the pooled estimate of six studies did not show a significant relationship between PD and the risk of developing CD in children (OR: 0.98, 95% CI: 0.81, 1.16, I2: 67.5%, P: 0.001).Summary: We found no evidence of an association between LBW and PD with the risk of developing CD in children.","PeriodicalId":50607,"journal":{"name":"Current Opinion in Gastroenterology","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Gastroenterology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/MOG.0000000000001074","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of review: Whether low birth weight (LBW) and preterm delivery (PD) are associated with the risk of developing celiac disease (CD) in children remains unclear. This systematic review and meta-analysis aimed to evaluate the association between LBW and PD with CD development in children.

Recent findings: We searched PubMed, Embase, Scopus, Web of Science, and Google Scholar databases based on the Mesh terms to find observational studies that investigated the association of LBW and PD with CD development in children up to July 18, 2024. This systematic review was based on the PRISMA 2020 checklist. Heterogeneity between studies was assessed with Cochran's Q and I2 tests. Meta-regression was used to control heterogeneity. Publication bias was evaluated using Egger's test. Finally, ten studies involving 3 434 290 participants were included. Based on 10 studies, the pooled prevalence of LBW was 6.4 per 1000 children with CD. A pooled estimate of ten studies did not show a significant relationship between LBW and the risk of developing CD in children [odds ratio (OR): 0.96, 95% confidence interval (CI): 0.76, 1.16, I2: 67.9%, P: 0.001). Also, the pooled estimate of six studies did not show a significant relationship between PD and the risk of developing CD in children (OR: 0.98, 95% CI: 0.81, 1.16, I2: 67.5%, P: 0.001).

Summary: We found no evidence of an association between LBW and PD with the risk of developing CD in children.

查看原文本刊更多论文

低出生体重和早产对儿童乳糜泻发展的影响：观察性研究的系统回顾和荟萃分析

综述目的：低出生体重（LBW）和早产（PD）是否与儿童发生乳糜泻（CD）的风险相关尚不清楚。本系统综述和荟萃分析旨在评估低体重和PD与儿童CD发展之间的关系。最近的发现：我们基于Mesh检索PubMed、Embase、Scopus、Web of Science和谷歌Scholar数据库，以查找调查LBW和PD与儿童CD发展关系的观察性研究，截止到2024年7月18日。本系统评价基于PRISMA 2020检查表。采用Cochran’s Q和I2检验评估研究间的异质性。采用元回归控制异质性。采用Egger’s检验评价发表偏倚。最后纳入10项研究，共3 434 290名受试者。根据10项研究，LBW的总患病率为每1000名CD患儿6.4人。10项研究的汇总估计未显示LBW与儿童发生CD的风险之间存在显著关系[优势比（OR）： 0.96, 95%可信区间（CI）： 0.76, 1.16, I2: 67.9%, P: 0.001)。此外，6项研究的汇总估计并未显示PD与儿童发生CD的风险之间存在显著关系（OR: 0.98, 95% CI: 0.81, 1.16, I2: 67.5%, P: 0.001）。总结：我们没有发现低体重和PD与儿童发生乳糜泻风险之间存在关联的证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Opinion in Gastroenterology 医学-胃肠肝病学

CiteScore

5.30

自引率

0.00%

发文量

137

审稿时长

6-12 weeks

期刊介绍： Published bimonthly and offering a unique and wide ranging perspective on the key developments in the field, each issue of Current Opinion in Gastroenterology features hand-picked review articles from our team of expert editors. With twelve disciplines published across the year – including gastrointestinal infections, nutrition and inflammatory bowel disease – every issue also contains annotated references detailing the merits of the most important papers.