Clinical characteristics of hospitalized male adolescents and young adults with avoidant/restrictive food intake disorder (ARFID).

IF 3.5 3区医学 Q2 NUTRITION & DIETETICS

Journal of Eating Disorders Pub Date : 2025-01-08 DOI:10.1186/s40337-024-01171-0

Jason M Nagata, Anita V Chaphekar, Patrick Low, Ruben Vargas, Kyle T Ganson, Anthony Nguyen, Sara M Buckelew, Andrea K Garber, Amanda E Downey

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引用次数: 0

Abstract

Background: Avoidant/restrictive food intake disorder (ARFID) may result in significant medical sequelae. Compared to youth with eating disorders like anorexia nervosa (AN), youth with ARFID tend to be younger and are more likely to be male. We aim to describe sex differences in clinical characteristics of youth hospitalized for medical complications of ARFID and compare their characteristics with youth hospitalized for anorexia nervosa.

Methods: This is a retrospective review of electronic medical records for youth with ARFID (N = 36; 13 male and 23 female) and AN (N = 355; 40 male and 315 female), including restricting and binge-eating/purging subtypes, aged 9-25 admitted to the inpatient UCSF Eating Disorders Program (2012-2020).

Results: A greater proportion of youth with ARFID were male compared to youth with AN (36.1% vs. 11.2%). Male youth with ARFID (mean age 15.5 ± 2.8) had lower heart rate nadir (49.2 vs. 57.6 beats per minute, p = .019) and lower total cholesterol (129.8 vs. 159.3 mg/dL, p = .008), but higher hemoglobin (13.9 vs. 13.0 g/dL, p = .015) and prescribed calories at discharge (3323 vs. 2817 kcal, p = .001) compared to females with ARFID. Males with AN, who on average had higher admission BMI than males with ARFID (17.3 vs. 15.5 kg/m², p = .013), required more (3785) kcal on discharge to restore medical stability than males with ARFID (3323 kcal). Compared to all youth with AN, youth with ARFID had lower body mass index (BMI, 15.7 vs. 17.0 kg/m², p = .001) and lower vitamin D (26.5 vs. 33.0 ng/mL, p = .003).

Conclusions: ARFID in males is associated with lower heart rate nadirs than in females with ARFID. Clinicians should be aware of unique medical complications in youth with ARFID compared to youth with AN.

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回避/限制性食物摄入障碍（ARFID）住院男性青少年和青年的临床特征

背景：回避/限制性食物摄入障碍（ARFID）可能导致严重的医学后遗症。与患有神经性厌食症（AN）等饮食失调的青少年相比，ARFID的青少年往往更年轻，而且更有可能是男性。我们的目的是描述因ARFID医学并发症住院的青少年临床特征的性别差异，并将其特征与因神经性厌食症住院的青少年进行比较。方法：回顾性分析青少年ARFID患者的电子病历(N = 36；男性13名，女性23名)和AN (N = 355；40名男性和315名女性)，包括限制型和暴食型/泻型，年龄9-25岁，住院于加州大学旧金山分校饮食失调项目（2012-2020）。结果：ARFID患者中男性的比例高于AN患者（36.1%对11.2%）。患有ARFID的男性青年（平均年龄15.5±2.8）与患有ARFID的女性相比，心率最低点（49.2对57.6次/分钟，p = 0.019）和总胆固醇（129.8对159.3 mg/dL, p = 0.008）较低，但血红蛋白（13.9对13.0 g/dL, p = 0.015）和出院时规定的卡路里（3323对2817 kcal， p = 0.001）较高。男性AN患者入院时平均BMI高于ARFID患者（17.3 vs. 15.5 kg/m2, p = 0.013），出院时恢复医疗稳定所需热量（3785）kcal，高于ARFID患者（3323 kcal）。与所有AN患者相比，ARFID患者的体重指数较低（BMI, 15.7 vs. 17.0 kg/m2, p = 0.001），维生素D较低（26.5 vs. 33.0 ng/mL, p = 0.003）。结论：ARFID男性患者的心率最低点低于ARFID女性患者。临床医生应该意识到青少年ARFID患者与青少年AN患者的独特医学并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Eating Disorders Neuroscience-Behavioral Neuroscience

CiteScore

5.30

自引率

17.10%

发文量

161

审稿时长

16 weeks

期刊介绍： Journal of Eating Disorders is the first open access, peer-reviewed journal publishing leading research in the science and clinical practice of eating disorders. It disseminates research that provides answers to the important issues and key challenges in the field of eating disorders and to facilitate translation of evidence into practice. The journal publishes research on all aspects of eating disorders namely their epidemiology, nature, determinants, neurobiology, prevention, treatment and outcomes. The scope includes, but is not limited to anorexia nervosa, bulimia nervosa, binge eating disorder and other eating disorders. Related areas such as important co-morbidities, obesity, body image, appetite, food and eating are also included. Articles about research methodology and assessment are welcomed where they advance the field of eating disorders.