Prevalence of traditional cardiovascular risk factors in high-risk Kyrgyzstan population as compared to Indians - An Indo-Kyrgyz cardiometabolic study.

IF 1.1 Q4 PRIMARY HEALTH CARE
Kamal Sharma, Shilpi Mohan, S A Hossain, Stuti Shah, Ashwati Konat, Komal Shah, Shubh Mehta, Jonsi Jayantkumar Tavethia, Jeel Narendra Sarvaiya, Saumya Joshi, Karan Shah, Dhruv Rakeshkumar Patel, Shlok Patel
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引用次数: 0

Abstract

Background: Cardiovascular diseases (CVDs) are one of the most prevalent causes of mortality worldwide, especially significant in low- and middle-income countries. Kyrgyzstan and India represent such nations that face a huge burden of CVD-related deaths globally. Understanding the prevalence of traditional cardiovascular risk factors (CVRFs) in these populations is critical for effective prevention and management strategies.

Methods: This is a multicentric, observational study where we compared the prevalence of CVRFs in high-risk populations from Kyrgyzstan and India. Data was collected from established ASCVD patients attending cardio-metabolic clinics at tertiary care centers between December 2021 and December 2023. Demographic characteristics and CVRFs, which encompassed diabetes, hypertension, lipid profile parameters, tobacco consumption, etc., were assessed. Statistical analysis was performed to identify significant differences between the cohorts.

Results: A total of 1552 individuals (772 from Kyrgyzstan, 750 from India) were studied. The Kyrgyzstan cohort had a significantly higher mean age and a greater proportion of females compared to the Indian cohort. The prevalence of tobacco consumption, hypertension, and diabetes was significantly higher in Kyrgyzstan than in India. Lipid profile analysis revealed greater level of LDL, HDL, and total cholesterol in the Kyrgyzstan cohort. Conversely, triglyceride levels were lower in Kyrgyz individuals. The Kyrgyzstan cohort also demonstrated better left ventricular systolic function compared to the Indian cohort.

Discussion: Our study highlights significant differences in the prevalence of traditional CVRFs between high-risk populations in Kyrgyzstan and India. Higher rates of tobacco consumption, hypertension, and diabetes in Kyrgyzstan signify the immediate need for targeted interventions to address these modifiable risk factors. Targeted public health programs focusing on these lifestyle modifications and efficacious management of CVRFs are crucial to reduce the burden of cardiovascular deaths in both countries.

与印度人相比,吉尔吉斯斯坦高危人群中传统心血管危险因素的患病率——一项印度-吉尔吉斯斯坦心脏代谢研究
背景:心血管疾病(cvd)是全世界最普遍的死亡原因之一,在低收入和中等收入国家尤为显著。吉尔吉斯斯坦和印度代表着在全球范围内面临着与心血管疾病相关的巨大死亡负担的国家。了解这些人群中传统心血管危险因素(cvrf)的患病率对于有效的预防和管理策略至关重要。方法:这是一项多中心观察性研究,我们比较了吉尔吉斯斯坦和印度高危人群中cvrf的患病率。数据收集自2021年12月至2023年12月期间在三级保健中心心脏代谢诊所就诊的ASCVD患者。评估了人口统计学特征和cvrf,包括糖尿病、高血压、血脂参数、烟草消费等。进行统计分析以确定队列之间的显著差异。结果:共调查1552人,其中吉尔吉斯斯坦772人,印度750人。与印度队列相比,吉尔吉斯斯坦队列的平均年龄和女性比例明显更高。吉尔吉斯斯坦的烟草消费、高血压和糖尿病患病率明显高于印度。脂质分析显示吉尔吉斯斯坦队列中LDL、HDL和总胆固醇水平较高。相反,吉尔吉斯人的甘油三酯水平较低。与印度队列相比,吉尔吉斯斯坦队列也表现出更好的左心室收缩功能。讨论:我们的研究强调了吉尔吉斯斯坦和印度高危人群之间传统cvrf患病率的显著差异。吉尔吉斯斯坦较高的烟草消费量、高血压和糖尿病率表明,迫切需要采取有针对性的干预措施,以解决这些可改变的风险因素。有针对性的公共卫生规划侧重于这些生活方式的改变和cvrf的有效管理,对于减少两国心血管死亡的负担至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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自引率
7.10%
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884
审稿时长
40 weeks
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