A laboratory feasibility study using a computer algorithm for anastomosis segmentation of epicardial ultrasonography images from distal coronary artery bypass anastomoses.
Alex Skovsbo Jørgensen, Martin Siemienski Andersen, Lasse Riis Østergaard, Samuel Emil Schmidt, Dorte Nøhr, Jan Jesper Andreasen
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引用次数: 0
Abstract
Background: The outcome of coronary artery bypass grafting (CABG) depends on several factors, including the quality of the distal anastomoses to the coronary arteries. Early graft failure may be caused by, e.g., technical suture failures, and such failures may be detected using intraoperative quality assessment. High-intensity epicardial ultrasonography (ECUS) allows anatomical visualization of the anastomoses during surgery, but currently, the images must be assessed manually. Here, we aim to describe an automatic quality assessment of distal coronary anastomoses using in-house software for vessel area and diameter extraction.
Methods: A postoperative, laboratory, investigational feasibility study comparing computer readings of longitudinal and transverse ultrasonographic images of distal coronary artery anastomoses with manual readings was performed, including ECUS images from 30 patients undergoing elective, isolated on-pump CABG. Vessel and anastomosis segmentation performance metrics from images obtained intraoperatively were compared to assess agreement between the manual and automatic segmentation methods. Scatter plots, the Dice coefficient and correlation analyses were used as measures of similarity between the two readings. p < 0.05 was considered significant.
Results: The number of dimensions of anastomotic vessel structures that are relevant for stenosis quantification and the Dice coefficient were 0.888 between the automatic and manual segmentations. The correlation coefficient between the manual and automatic stenotic rates was 0.674.
Conclusions: An anastomosis segmentation software for automatic and objective extraction of the anatomical dimensions of relevant distal coronary anastomotic structures from ECUS images obtained during CABG was developed. The framework allows for quantifying stenotic in the anastomotic structures and has the potential to assist surgeons during quality assessment of coronary anastomoses when the described segmentation of vessels and anastomoses is available for real-time epicardial ultrasonography use during surgery.
Trial registration: The study was registered on September 29, 2016, before enrolment of the first participant (ClinicalTrials.gov ID: NCT02919124).
期刊介绍：
Journal of Cardiothoracic Surgery is an open access journal that encompasses all aspects of research in the field of Cardiology, and Cardiothoracic and Vascular Surgery. The journal publishes original scientific research documenting clinical and experimental advances in cardiac, vascular and thoracic surgery, and related fields.
Topics of interest include surgical techniques, survival rates, surgical complications and their outcomes; along with basic sciences, pediatric conditions, transplantations and clinical trials.
Journal of Cardiothoracic Surgery is of interest to cardiothoracic and vascular surgeons, cardiothoracic anaesthesiologists, cardiologists, chest physicians, and allied health professionals.
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